Evidence map›Paper›PMID 38140592›Full record

ArticleViruses2023

Defining the Cynomolgus Macaque (

Crystal W Burke, Christina L Gardner, Aimee I Goodson, Ashley E Piper, Rebecca A Erwin-Cohen, Charles E White, Pamela J Glass

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Crystal W BurkeVirology Division, U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.ORCID 0000-0001-8734-8912
Christina L GardnerVirology Division, U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.
Aimee I GoodsonVirology Division, U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.
Ashley E PiperVirology Division, U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.
Rebecca A Erwin-CohenVirology Division, U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.ORCID 0000-0002-5838-9026
Charles E WhiteStatistics Division, U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.ORCID 0000-0003-4359-9984
Pamela J GlassVirology Division, U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.
United States Army Medical Research Institute of Infectious Diseases · US

Funding

Defense Threat Reduction Agency CB-CALL12-VAXV2-2-0175
6 · The paper itself

Abstract

Venezuelan equine encephalitis virus (VEEV) outbreaks occur sporadically. Additionally, VEEV has a history of development as a biothreat agent. Yet, no FDA-approved vaccine or therapeutic exists for VEEV disease. The sporadic outbreaks present a challenge for testing medical countermeasures (MCMs) in humans; therefore, well-defined animal models are needed for FDA Animal Rule licensure. The cynomolgus macaque (CM) model has been studied extensively at high challenge doses of the VEEV Trinidad donkey strain (>1.0 × 10

Indexed as

Encephalitis Virus, Venezuelan EquineEncephalomyelitis, Venezuelan EquineViral VaccinesAnimalsDisease Models, AnimalHorsesHumansMacaca fascicularisViremiaViral Vaccinesaerosol exposureanimal modelcynomolgus macaquemedical countermeasuresnonhuman primatesstudy designVenezuelan equine encephalitis virus

Identifiers

PMID38140592
PMCPMC10748030
OpenAlexW4389132199

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.