Evidence map›Paper›PMID 38140534›Full record

ArticleViruses2023

Experimental Infection of Chickens with H5N8 High Pathogenicity Avian Influenza Viruses Isolated in Japan in the Winter of 2020-2021.

Saki Sakuma, Taichiro Tanikawa, Ryota Tsunekuni, Junki Mine, Asuka Kumagai, Kohtaro Miyazawa, Yoshihiro Takadate, Yuko Uchida

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Saki SakumaNational Institute of Animal Health, National Agriculture and Food Research Organization, 3-1-5 Kannondai, Tsukuba 305-0856, Ibaraki, Japan.
Taichiro TanikawaNational Institute of Animal Health, National Agriculture and Food Research Organization, 3-1-5 Kannondai, Tsukuba 305-0856, Ibaraki, Japan.ORCID 0000-0002-8649-7278
Ryota TsunekuniNational Institute of Animal Health, National Agriculture and Food Research Organization, 3-1-5 Kannondai, Tsukuba 305-0856, Ibaraki, Japan.
Junki MineNational Institute of Animal Health, National Agriculture and Food Research Organization, 3-1-5 Kannondai, Tsukuba 305-0856, Ibaraki, Japan.ORCID 0000-0002-1603-8471
Asuka KumagaiNational Institute of Animal Health, National Agriculture and Food Research Organization, 3-1-5 Kannondai, Tsukuba 305-0856, Ibaraki, Japan.
Kohtaro MiyazawaNational Institute of Animal Health, National Agriculture and Food Research Organization, 3-1-5 Kannondai, Tsukuba 305-0856, Ibaraki, Japan.ORCID 0000-0002-0318-7275
Yoshihiro TakadateNational Institute of Animal Health, National Agriculture and Food Research Organization, 3-1-5 Kannondai, Tsukuba 305-0856, Ibaraki, Japan.ORCID 0009-0000-5132-1988
Yuko UchidaNational Institute of Animal Health, National Agriculture and Food Research Organization, 3-1-5 Kannondai, Tsukuba 305-0856, Ibaraki, Japan.ORCID 0000-0002-5833-5917
National Agriculture and Food Research Organization · JP

Funding

the Ministry of Agriculture, Forestry, and Fisheries of Japan JPJ008617.18065101, JPJ008617.23812859
6 · The paper itself

Abstract

During the winter of 2020-2021, numerous outbreaks of high pathogenicity avian influenza (HPAI) were caused by viruses of the subtype H5N8 in poultry over a wide region in Japan. The virus can be divided into five genotypes-E1, E2, E3, E5, and E7. The major genotype responsible for the outbreaks was E3, followed by E2. To investigate the cause of these outbreaks, we experimentally infected chickens with five representative strains of each genotype. We found that the 50% chicken infectious dose differed by up to 75 times among the five strains, and the titer of the E3 strains (10

Indexed as

Influenza A Virus, H5N8 SubtypeInfluenza in BirdsPoultry DiseasesAnimalsChickensDisease OutbreaksJapanSeasonsVirulenceavian fluchickenhigh pathogenicity avian influenza virusinfectivityJapantransmissibilityvirulence

Identifiers

PMID38140534
PMCPMC10748181
OpenAlexW4388928709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.