Evidence map›Paper›PMID 38140329›Full record

ArticleNutrients2023

Higher Short-Chain Fermentable Carbohydrates Are Associated with Lower Body Fat and Higher Insulin Sensitivity in People with Prediabetes.

Natural H S Chu, Jie He, Kathy H T Leung, Ronald C W Ma, Jimmy Y S Lee, Jane Varney, Juliana C N Chan, Jane G Muir, Elaine Chow

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

Natural H S ChuDepartment of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.ORCID 0000-0003-3678-6749
Jie HeDepartment of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.
Kathy H T LeungDepartment of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.
Ronald C W MaDepartment of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.ORCID 0000-0002-1227-803X
Jimmy Y S LeeDepartment of Gastroenterology, Monash University and Alfred Hospital, Melbourne, VIC 3004, Australia.
Jane VarneyDepartment of Gastroenterology, Monash University and Alfred Hospital, Melbourne, VIC 3004, Australia.
Juliana C N ChanDepartment of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.ORCID 0000-0003-1325-1194
Jane G MuirDepartment of Gastroenterology, Monash University and Alfred Hospital, Melbourne, VIC 3004, Australia.
Elaine ChowDepartment of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.ORCID 0000-0002-4147-3387
Chinese University of Hong Kong · HKMonash University · AU

Funding

Health and Medical Research Fund 17180431Hong Kong College of Physicians Young Investigators Research Grant NA
6 · The paper itself

Abstract

The quality of carbohydrates has metabolic consequences in people with prediabetes. However, the causality of short-chain fermentable carbohydrate intakes and metabolic parameters has not been explored in the prediabetic or diabetic population. We investigated associations between different types of carbohydrates, including fermentable oligosaccharides, disaccharides, monosaccharides, polyols (FODMAPs), and polysaccharides (dietary fibre), and body composition and glucose/insulin responses in subjects with prediabetes. In this prospective cross-sectional study, 177 subjects with impaired glucose tolerance (IGT) (mean age: 60 (54-62) years, 41% men) underwent an assessment of body composition and completed six-point oral glucose tolerance tests (OGTT), Homeostatic Model Assessment of Insulin Resistance (HOMA2-IR), insulin sensitivity, detailed 3-day food records, and physical activity questionnaire. Daily habitual FODMAP intake decreased progressively with increasing BMI, ranging from 7.9 (6.2-12.7) g/d in subjects with normal BMI and 6.6 (4.6-9.9) g/d in subjects with overweight to 5.8 (3.8-9.0) g/d in subjects with obesity (

Indexed as

Glucose IntoleranceInsulin ResistancePrediabetic StateAdipose TissueCross-Sectional StudiesFemaleHexosesHumansMaleMiddle AgedOligosaccharidesProspective StudiesHexosesOligosaccharidesbody fatdiabetesFODMAPsimpaired glucose tolerance (IGT)insulin sensitivityobesity

Identifiers

PMID38140329
PMCPMC10745595
OpenAlexW4389546437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.