ReviewNutrients2023
The Health Effects of Low Glycemic Index and Low Glycemic Load Interventions on Prediabetes and Type 2 Diabetes Mellitus: A Literature Review of RCTs.
Review in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effect of dietary glycemic index on insulin resistance in adults without diabetes mellitus: a systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- Optimizing carbohydrate quality: a path to better health for women with PCOS.Frontiers in nutrition · 2025Pooled it
- Efficacy of diabetes-specific partial meal replacement on glycemic and weight control in type 2 diabetes: A randomized controlled trial.Diabetes, obesity & metabolism · 2025Trial
- Review
- The Effect of Low Glycemic Load Diet on Central Obesity and Lipid Related Metabolic Abnormalities in T2DM Patients Is Comparable to That of Energy-Restricted Diet: A Randomized, Open, Parallel Controlled Study.Food science & nutrition · 2026Article
- The Effect of Including 1 Avocado Daily in a Habitual Diet on the Glycemic Index and Glycemic Load in Free-Living Adults with Overweight/Obesity.Current developments in nutrition · 2026Article
- Global risk factors, epidemiology, and disease burden of type 2 diabetes.Science China. Life sciences · 2026Review
- Effectiveness of a culturally adapted group-based lifestyle intervention in reducing cardiovascular risk factors in a high-risk Latin American population.Translational behavioral medicine · 2026Article
- A New Approach with Agri-Food By-Products: A Case Study of Fortified Fresh Pasta with Red Onion Peels.Foods (Basel, Switzerland) · 2025Article
- Biosynthesized Silver Nanoparticles and Their Antidiabetic Potential.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Bioactive Potential of Tocosh Supplemented with Selenium-Enriched Saccharomyces Cerevisiae Biomass.Foods (Basel, Switzerland) · 2025Article
- Effects of 12 nutritional interventions on type 2 diabetes: a systematic review with network meta-analysis of randomized trials.Nutrition & metabolism · 2025Article
- Associations of carbohydrate quality and cardiovascular risk factors vary among diabetes subtypes.Cardiovascular diabetology · 2025Observational
- Novel Fibre-Rich Breads Yield Improved Glucose Release Curves and Are Well Accepted by Children in Primary School Breakfast Clubs.Nutrients · 2025Article
- Acceptance and feasibility of novel staple foods among individuals with type 2 diabetes in Singapore: a mixed methods study.Frontiers in nutrition · 2025Article
- Metabolic profiles of captive Asian elephants (Elephas maximus) in Lao PDR and Thailand.PloS one · 2025Article
- Development of Whole-Grain Rice Lines Exhibiting Low and Intermediate Glycemic Index with Decreased Amylose Content.Foods (Basel, Switzerland) · 2024Article
- Acute Consumption of Cooked Green Banana Pulp Beverage (Musa cavendishii) Decreases Plasma Glucose in Healthy Women: A Cross-Sectional Controlled Study.Plant foods for human nutrition (Dordrecht, Netherlands) · 2024Article
- A low-carbohydrate, high-fat diet leads to unfavorable changes in blood lipid profiles compared to carbohydrate-rich diets with different glycemic indices in recreationally active men.Frontiers in nutrition · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Diets with a low glycemic index (GI) and a low glycemic load (GL) can improve glycemic control, blood lipids, blood pressure and BMI in prediabetes and type 2 diabetes (T2DM), but evidence regarding other aspects of cardiometabolic health is limited. We searched the literature for RCTs published from 2013 to 2023 and reviewed the evidence on low-GI/GL diets and their effects on different aspects of health in prediabetes and T2DM, aiming to build a report on all relevant outcomes included in the studies. We included 14 RCTs with 1055 participants, who were mostly middle-aged individuals with T2DM. Interventions were mostly low GI and lasted 1-36 months. Low-GI/GL foods and diets showed benefits in terms of short-term glycemic control, weight and adiposity. Longer-term trials would be necessary to determine whether these benefits persist over time and/or lead to lower CVD risk and mortality. Effects on lipid profile were inconsistent. Some studies also reported positive effects of low-GI/GL interventions on blood pressure, inflammatory biomarkers, renal function and gut microbiota composition. Future trials should focus on some of these novel outcome measures, which may provide important insights into the metabolic effects of low-GI diets on individuals with diabetes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.