ArticleVaccines2023
Biological Characteristics of Feline Calicivirus Epidemic Strains in China and Screening of Broad-Spectrum Protective Vaccine Strains.
Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 8 citations in OpenAlex.
- Isolation, Molecular Characterization, and Pathogenicity Evaluation of a Genotype GI Feline Calicivirus Isolate.Microorganisms · 2026Article
- Construction of Reverse Genetics System for Feline Calicivirus FCV-BJ616 and Proteomic Analysis.MicrobiologyOpen · 2026Article
- Isolation and identification of a genotype F bovine enterovirus in western China.Microbiology spectrum · 2026Article
- Epidemiology, Phylogenetic Divergence, and Differential Pathogenicity of Feline RespiratoryTransboundary and emerging diseases · 2026Article
- A novel replication-deficient FCV vaccine provides strong immune protection in cats.Journal of virology · 2025Article
- Discovery of a novel genogroup feline calicivirus through molecular evolution in group-housed cats in China.Scientific reports · 2025Article
- Isolation, Identification, and Genetic Evolution Analysis ofInternational journal of molecular sciences · 2025Article
- Novel Strain-Based Triple Inactivated Vaccine Confers Rapid Neutralizing Immunity to Feline Multisystemic Pathogens With Two-Dose Regimen.Transboundary and emerging diseases · 2025Article
- Screening and Immune Efficacy Evaluation of Antigens with Protection Against Feline Calicivirus.Vaccines · 2024Article
Corrections and comments
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Authors and funding
13 authors at 4 institutions in 2 countries.
Funding
Abstract
Feline calicivirus (FCV) is one of the most important pathogens causing upper respiratory tract diseases in cats, posing a serious health threat to these animals. At present, FCV is mainly prevented through vaccination, but the protective efficacy of vaccines in China is limited. In this study, based on the differences in capsid proteins of isolates from different regions in China, as reported in our previous studies, seven representative FCV epidemic strains were selected and tested for their viral titers, virulence, immunogenicity, and extensive cross-protection. Subsequently, vaccine strains were selected to prepare inactivated vaccines. The whole-genome sequencing and analysis results showed that these seven representative FCV strains and 144 reference strains fell into five groups (A, B, C, D, and E). The strains isolated in China mainly fall into groups C and D, exhibiting regional characteristics. These Chinese isolates had a distant evolutionary relationship and low homology with the current FCV-255 vaccine strain. The screened FCV-HB7 and FCV-HB10 strains displayed desirable in vitro culture characteristics, with the highest virus proliferation titers (10
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.