Evidence map›Paper›PMID 38140215›Full record

ArticleVaccines2023

The Group A Streptococcal Vaccine Candidate VAX-A1 Protects against Group B

Sinead McCabe, Elisabet Bjånes, Astrid Hendriks, Zhen Wang, Nina M van Sorge, Lucy Pill-Pepe, Leslie Bautista, Ellen Chu, Jeroen D C Codée, Jeff Fairman and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Sinead McCabeDivision of Host-Microbe Systems and Therapeutics, Department of Pediatrics, University of California San Diego, La Jolla, CA 92093, USA.ORCID 0009-0005-1910-9780
Elisabet BjånesDivision of Host-Microbe Systems and Therapeutics, Department of Pediatrics, University of California San Diego, La Jolla, CA 92093, USA.ORCID 0000-0002-2747-7699
Astrid HendriksDepartment of Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Zhen WangLeiden Institute of Chemistry, Leiden University, 2333 CC Leiden, The Netherlands.
Nina M van SorgeDepartment of Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0002-2695-5863
Lucy Pill-PepeVaxcyte, Inc., San Carlos, CA 94070, USA.
Leslie BautistaVaxcyte, Inc., San Carlos, CA 94070, USA.
Ellen ChuVaxcyte, Inc., San Carlos, CA 94070, USA.
Jeroen D C CodéeLeiden Institute of Chemistry, Leiden University, 2333 CC Leiden, The Netherlands.
Jeff FairmanVaxcyte, Inc., San Carlos, CA 94070, USA.
Neeraj KapoorVaxcyte, Inc., San Carlos, CA 94070, USA.
Satoshi UchiyamaDivision of Host-Microbe Systems and Therapeutics, Department of Pediatrics, University of California San Diego, La Jolla, CA 92093, USA.
Victor NizetDivision of Host-Microbe Systems and Therapeutics, Department of Pediatrics, University of California San Diego, La Jolla, CA 92093, USA.ORCID 0000-0003-3847-0422
University of California San Diego · USAmsterdam University Medical Centers · NLLeiden University · NL

Funding

Identifying the Most Effective Adjuvant(s) for Leading Group A Streptococcal Vaccine Antigens in Preclinical Mouse and Nonhuman Primate ModelsR01AI173689 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Victor Nizet, Mark Joseph Walker · 2023 to 2026
$2.8M
NIAID NIH HHS R01 AI173689
6 · The paper itself

Abstract

Group B

Indexed as

C5a peptidaseconjugate vaccinecross-protective immunitygroup A Streptococcusgroup B StreptococcusStreptococcus agalactiaeStreptococcus pyogenesvaccinevirulence factor

Identifiers

PMID38140215
PMCPMC10747066
OpenAlexW4389286249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.