Evidence map›Paper›PMID 38140130›Full record

ArticlePharmaceutics2023

Preparation of

Nan Liu, Jie Xiao, Ling-He Zang, Peng Quan, Dong-Chun Liu

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nan LiuSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Jie XiaoSchool of Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.
Ling-He ZangSchool of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang 110016, China.
Peng QuanSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Dong-Chun LiuSchool of Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.ORCID 0000-0003-0732-7623
Shenyang Pharmaceutical University · CN

Funding

China Medicine Education Association 2022KTZ014higher education institutions of Liaoning Provincial Department of Education 2111520169National Key R&D Program of China 2022YFE0111600
6 · The paper itself

Abstract

Crocetin (CRT), an active compound isolated from saffron, exhibits several pharmacological activities, including anti-tumor and immune-regulatory activities, and is effective against myocardial ischemia and coronary heart disease; however, its low stability and solubility limit its clinical application. Therefore, we investigated CRT inclusion complexes (ICs) with three cyclodextrins-α-CD, HP-β-CD, and γ-CD-suitable for oral administration prepared using an ultrasonic method. Fourier transform infrared spectroscopy and powder X-ray diffraction indicated that the crystalline state of CRT in ICs disappeared, and intermolecular interactions were observed between CRT and CDs.

Indexed as

crocetindissolutioninclusion complexoral bioavailabilitysolubilitystability

Identifiers

PMID38140130
PMCPMC10747661
OpenAlexW4389893854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.