Evidence map›Paper›PMID 38140013›Full record

ArticlePharmaceutics2023

Plant-Derived Nanocellulose with Antibacterial Activity for Wound Healing Dressing.

Gabriela Mădălina Oprică, Denis Mihaela Panaitescu, Brînduşa Elena Lixandru, Catalina Diana Uşurelu, Augusta Raluca Gabor, Cristian-Andi Nicolae, Radu Claudiu Fierascu, Adriana Nicoleta Frone

Abstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Emerging Role of Plant-Derived Nanostructures in Nanomedicine.International journal of nanomedicine · 2025
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gabriela Mădălina OpricăNational Institute for Research and Development in Chemistry and Petrochemistry, 202 Spl. Independentei, 060021 Bucharest, Romania.
Denis Mihaela PanaitescuNational Institute for Research and Development in Chemistry and Petrochemistry, 202 Spl. Independentei, 060021 Bucharest, Romania.ORCID 0000-0003-3352-0929
Brînduşa Elena LixandruCantacuzino National Medical-Military Institute for Research and Development, 103 Spl. Independentei, 050096 Bucharest, Romania.
Catalina Diana UşureluNational Institute for Research and Development in Chemistry and Petrochemistry, 202 Spl. Independentei, 060021 Bucharest, Romania.
Augusta Raluca GaborNational Institute for Research and Development in Chemistry and Petrochemistry, 202 Spl. Independentei, 060021 Bucharest, Romania.ORCID 0000-0003-3785-2314
Cristian-Andi NicolaeNational Institute for Research and Development in Chemistry and Petrochemistry, 202 Spl. Independentei, 060021 Bucharest, Romania.
Radu Claudiu FierascuNational Institute for Research and Development in Chemistry and Petrochemistry, 202 Spl. Independentei, 060021 Bucharest, Romania.ORCID 0000-0003-4224-9157
Adriana Nicoleta FroneNational Institute for Research and Development in Chemistry and Petrochemistry, 202 Spl. Independentei, 060021 Bucharest, Romania.ORCID 0000-0001-6232-886X

Funding

Ministerul Cercetării și Inovării PN-III-P2-2.1-PED-2021-2559 (BIOPLASM) contract 632PED/2022.
6 · The paper itself

Abstract

The medical sector is one of the biggest consumers of single-use materials, and while the insurance of sterile media is non-negotiable, the environmental aspect is a chronic problem. Nanocellulose (NC) is one of the safest and most promising materials that can be used in medical applications due to its valuable properties like biocompatibility and biodegradability, along with its good mechanical properties and high water uptake capacity. However, NC has no bactericidal activity, which is a critical need for the effective prevention of infections in chronic diabetic wound dressing applications. Therefore, in this work, a natural product, propolis extract (PE), was used as an antibacterial agent, in different amounts, together with NC to obtain sponge-like structures (NC/PE). The scanning electron microscope (SEM) images showed well-impregnated cellulose fibers and a more compact structure with the addition of PE. According to the thermogravimetric analysis (TGA), the samples containing PE underwent thermal degradation before the unmodified NC due to the presence of volatile compounds in the extract. However, the peak degradation temperature in the first derivative thermogravimetric curves was higher for all the sponges containing PE when compared to the unmodified NC. The antibacterial efficacy of the samples was tested against

Indexed as

antibacterialcellulose nanofiberspropolisspongeswound dressing

Identifiers

PMID38140013
PMCPMC10747278

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.