Evidence map›Paper›PMID 38140011›Full record

ArticlePharmaceutics2023

Shock Wave-Activated Silver-Loaded Biopolymer Implant Coating Eliminates

Martin Schulze, Melanie Nonhoff, Julian Hasselmann, Manfred Fobker, Silke Niemann, Christoph Theil, Georg Gosheger, Jan Puetzler

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Martin SchulzeDepartment of General Orthopedics and Tumor Orthopedics, Muenster University Hospital, 48149 Münster, Germany.ORCID 0000-0003-2899-1558
Melanie NonhoffDepartment of General Orthopedics and Tumor Orthopedics, Muenster University Hospital, 48149 Münster, Germany.ORCID 0009-0000-4529-3159
Julian HasselmannDepartment of General Orthopedics and Tumor Orthopedics, Muenster University Hospital, 48149 Münster, Germany.ORCID 0000-0002-5334-5171
Manfred FobkerCentral Laboratory, Muenster University Hospital, Albert-Schweitzer-Campus 1, 48149 Münster, Germany.
Silke NiemannInstitute of Medical Microbiology, Muenster University Hospital, 48149 Münster, Germany.ORCID 0000-0002-9807-2541
Christoph TheilDepartment of General Orthopedics and Tumor Orthopedics, Muenster University Hospital, 48149 Münster, Germany.
Georg GoshegerDepartment of General Orthopedics and Tumor Orthopedics, Muenster University Hospital, 48149 Münster, Germany.
Jan PuetzlerDepartment of General Orthopedics and Tumor Orthopedics, Muenster University Hospital, 48149 Münster, Germany.ORCID 0000-0002-4943-3398
University Hospital Münster · DE

Funding

Else Kröner-Fresenius-Stiftung 2021_EKEA.129IMF Faculty programm University of Muenster I-SC122008
6 · The paper itself

Abstract

Bacterial biofilms on foreign surfaces are considered a primary cause of implant-related infections, which are challenging to treat. A new implant coating was developed, containing anti-infective silver within a biocompatible polymer carrier substance. In addition to its passive effect on the implant surface, highly concentrated anti-infective silver can be released as needed via the application of high-energy shock waves. This intervention could be applied transcutaneously in a clinical setting without the need for additional surgery. We investigated the inhibition of biofilm formation and the effectiveness of eradication after activation of the coating via shock waves in an in vitro biofilm model using

Indexed as

anti-infective silverbiofilm preventionextracorporeal shock wavesimplant coatingimplant-related infection

Identifiers

PMID38140011
PMCPMC10747100
OpenAlexW4389051575

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.