Evidence map›Paper›PMID 38139998›Full record

ArticlePharmaceutics2023

Fennel Essential Oil as a Complementary Therapy in the Management of Diabetes.

Ruxandra Ștefănescu, Bianca-Eugenia Ősz, Andrada Pintea, Eszter Laczkó-Zöld, Amelia Tero-Vescan, Camil-Eugen Vari, Emoke Fulop, Iuliana Blaș, Szende Vancea

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Intranasal essential oils in therapy: advances in clinical applications and delivery mechanisms.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2026
    Review
  2. Article
  3. Article
  4. Antidiabetic effects of fennel leaf aqueous extract in alloxan-induced diabetic rats.Journal of pharmaceutical health care and sciences · 2025
    Article
  5. Advances in essential oils for metabolic diseases.Frontiers in endocrinology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ruxandra ȘtefănescuDepartment of Pharmacognosy and Phytotherapy, Faculty of Pharmacy, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mures, 38 Gheorghe Marinescu Street, 540139 Târgu Mures, Romania.ORCID 0000-0002-3346-3867
Bianca-Eugenia ŐszDepartment of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, 38 Gheorghe Marinescu Street, 540139 Târgu Mures, Romania.
Andrada PinteaFaculty of Pharmacy, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, 38 Gheorghe Marinescu Street, 540139 Târgu Mures, Romania.
Eszter Laczkó-ZöldDepartment of Pharmacognosy and Phytotherapy, Faculty of Pharmacy, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mures, 38 Gheorghe Marinescu Street, 540139 Târgu Mures, Romania.ORCID 0000-0002-8189-1129
Amelia Tero-VescanDepartment of Biochemistry, Faculty of Medicine, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, 38 Gheorghe Marinescu Street, 540139 Târgu Mures, Romania.
Camil-Eugen VariDepartment of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, 38 Gheorghe Marinescu Street, 540139 Târgu Mures, Romania.ORCID 0000-0003-0880-6212
Emoke FulopEmergency County Hospital Târgu Mureș, Department of Pathology, 50 Gh. Marinescu Street, 540136 Târgu Mureș, Romania.
Iuliana BlașFaculty of Pharmacy, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, 38 Gheorghe Marinescu Street, 540139 Târgu Mures, Romania.
Szende VanceaLegal Medicine Service, Emergency County Hospital Miercurea Ciuc, 530173 Miercurea Ciuc, Romania.
Universitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș · ROClinical Emergency Hospital Bucharest · ROSpitalul Clinic Judetean de Urgenta Târgu Mureş · RO

Funding

George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mureș 163 /7/ 10.01.2023
6 · The paper itself

Abstract

Diabetes is a serious pathology that affects a significant number of people worldwide. Its progression is rapid and leads to serious complications if glycemic control is missing. The micro and macrovascular complications of diabetes produce disabilities over time that affect the daily lives of patients. The major challenge of diabetes therapy is to reach a stable glycemic state and to delay the onset of specific complications. Aromatherapy is considered an alternative or complementary therapy, but in recent years, there has been a tendency to overuse essential oils. The present study was designed to evaluate and compare the effects produced by the topical and oral administration of fennel essential oil to diabetic rats. Eighteen compounds in fennel essential oil were identified by gas chromatography-mass spectrometry (GC-MS) analysis. The major compounds were

Indexed as

aromatherapydiabetesfennel essential oil

Identifiers

PMID38139998
PMCPMC10747567
OpenAlexW4388928778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.