Evidence map›Paper›PMID 38139919›Full record

ReviewPolymers2023

Bioabsorbable Composites Based on Polymeric Matrix (PLA and PCL) Reinforced with Magnesium (Mg) for Use in Bone Regeneration Therapy: Physicochemical Properties and Biological Evaluation.

Rubén García-Sobrino, Marta Muñoz, Elías Rodríguez-Jara, Joaquín Rams, Belén Torres, Sandra C Cifuentes

Open access · goldAbstract readReview
In one paragraph

Review in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Current developments in orthopaedic implant technology.Journal of orthopaedic surgery and research · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rubén García-SobrinoDepartment of Applied Mathematics, Materials Science and Engineering and Electronic Technology, Universidad Rey Juan Carlos, Calle Tulipán s/n, 28933 Móstoles, Spain.ORCID 0000-0002-9900-4241
Marta MuñozDepartment of Applied Mathematics, Materials Science and Engineering and Electronic Technology, Universidad Rey Juan Carlos, Calle Tulipán s/n, 28933 Móstoles, Spain.ORCID 0000-0002-4164-2224
Elías Rodríguez-JaraInstituto de Cerámica y Vidrio, Consejo Superior de Investigaciones Científicas (CSIC), Campus de Cantoblanco, c/Kelsen 5, 28049 Madrid, Spain.ORCID 0000-0002-4068-5978
Joaquín RamsDepartment of Applied Mathematics, Materials Science and Engineering and Electronic Technology, Universidad Rey Juan Carlos, Calle Tulipán s/n, 28933 Móstoles, Spain.ORCID 0000-0003-0837-3437
Belén TorresDepartment of Applied Mathematics, Materials Science and Engineering and Electronic Technology, Universidad Rey Juan Carlos, Calle Tulipán s/n, 28933 Móstoles, Spain.ORCID 0000-0002-8123-7952
Sandra C CifuentesDepartment of Applied Mathematics, Materials Science and Engineering and Electronic Technology, Universidad Rey Juan Carlos, Calle Tulipán s/n, 28933 Móstoles, Spain.ORCID 0000-0001-9779-369X
Universidad Rey Juan Carlos · ESConsejo Superior de Investigaciones Científicas · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Improvements in Tissue Engineering and Regenerative Medicine (TERM)-type technologies have allowed the development of specific materials that, together with a better understanding of bone tissue structure, have provided new pathways to obtain biomaterials for bone tissue regeneration. In this manuscript, bioabsorbable materials are presented as emerging materials in tissue engineering therapies related to bone lesions because of their ability to degrade in physiological environments while the regeneration process is completed. This comprehensive review aims to explore the studies, published since its inception (2010s) to the present, on bioabsorbable composite materials based on PLA and PCL polymeric matrix reinforced with Mg, which is also bioabsorbable and has recognized osteoinductive capacity. The research collected in the literature reveals studies based on different manufacturing and dispersion processes of the reinforcement as well as the physicochemical analysis and corresponding biological evaluation to know the osteoinductive capacity of the proposed PLA/Mg and PCL/Mg composites. In short, this review shows the potential of these composite materials and serves as a guide for those interested in bioabsorbable materials applied in bone tissue engineering.

Indexed as

bioabsorbable materialsbone regenerationcompositesmagnesiumPCLPLA

Identifiers

PMID38139919
PMCPMC10747080
OpenAlexW4389545512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.