Evidence map›Paper›PMID 38139807›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

Span 60/Cholesterol Niosomal Formulation as a Suitable Vehicle for Gallic Acid Delivery with Potent In Vitro Antibacterial, Antimelanoma, and Anti-Tyrosinase Activity.

Sara Zolghadri, Ali Ghanbari Asad, Fatemeh Farzi, Fatemeh Ghajarzadeh, Zeinab Habibi, Mahdie Rahban, Samaneh Zolghadri, Agata Stanek

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
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  7. Review
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  10. Stearyl amine tailored spanlastics embedded within tetronicDaru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2025
    Article
  11. Article
  12. Article
  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sara ZolghadriDepartment of Chemistry, Jahrom Branch, Islamic Azad University, Jahrom 7414785318, Iran.
Ali Ghanbari AsadDepartment of Medical Biotechnology, Fasa University of Medical Sciences, Fasa 7461686688, Iran.ORCID 0000-0002-1725-1426
Fatemeh FarziDepartment of Biology, Jahrom Branch, Islamic Azad University, Jahrom 7414785318, Iran.
Fatemeh GhajarzadehDepartment of Biology, Jahrom Branch, Islamic Azad University, Jahrom 7414785318, Iran.
Zeinab HabibiDepartment of Biology, Jahrom Branch, Islamic Azad University, Jahrom 7414785318, Iran.
Mahdie RahbanNeuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman 7616913555, Iran.ORCID 0000-0003-2924-9101
Samaneh ZolghadriDepartment of Biology, Jahrom Branch, Islamic Azad University, Jahrom 7414785318, Iran.ORCID 0000-0003-4060-328X
Agata StanekDepartment and Clinic of Internal Medicine, Angiology and Physical Medicine, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Batorego 15 St, 41-902 Bytom, Poland.ORCID 0000-0001-6939-9898

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural compounds such as gallic acid (GA) have attracted more attention in cosmetic and pharmaceutical skin care products. However, the low solubility and poor stability of GA have limited its application. This study aimed to synthesize and characterize the GA niosomal dispersion (GAN) and investigate the potential of an optimal formulation as a skin drug delivery system for GA. For this purpose, GAN formulations were synthesized using the thin layer evaporation method with different molar ratios of Tween 60/Span 60, along with a constant molar ratio of polyethylene glycol 4000 (PEG-4000) and cholesterol in a methanol and chloroform solvent (1:4

Indexed as

drug deliveryentrapment efficiencygallic acid niosomesmelanomaSpan 60tyrosinase inhibitor

Identifiers

PMID38139807
PMCPMC10748266

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.