Evidence map›Paper›PMID 38139793›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

The Chemoprevention Effects of Two Herbal Mixtures on Chemically Induced Lung Tumorigenesis in Mice.

Chunjie Li, Yian Wang, Song Gao, Ming Hu, Ming You

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Chunjie LiDivision of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH 43210, USA.
Yian WangCenter for Cancer Prevention, Houston Methodist Cancer Center, Houston Methodist Research Institute, Weill Cornell College of Medicine, Houston, TX 77030, USA.
Song GaoDepartment of Pharmaceutical Science, College of Pharmacy and Health Science, Texas Southern University, Houston, TX 77004, USA.ORCID 0000-0003-2361-3494
Ming HuDepartment of Pharmacological and Pharmaceutical Science, College of Pharmacy, University of Houston, Houston, TX 77204, USA.ORCID 0000-0002-2744-6294
Ming YouCenter for Cancer Prevention, Houston Methodist Cancer Center, Houston Methodist Research Institute, Weill Cornell College of Medicine, Houston, TX 77030, USA.
Houston Methodist · USTexas Southern University · USThe Ohio State University · USUniversity of Houston · US

Funding

Transfer Application - R01 CA223804 - Chemoimmunoprevention of EGFR-Driven Non-Small Cell Lung CancerR01CA223804 · NCI · METHODIST HOSPITAL RESEARCH INSTITUTE · PI WANG, LI LILY, YOU, MING · 2018 to 2022
$3.3M
Chemoprevention of Lung Cancer with Mitochondria-Targeted HonokiolR01CA208648 · NCI · METHODIST HOSPITAL RESEARCH INSTITUTE · PI KALYANARAMAN, BALARAMAN, YOU, MING · 2017 to 2021
$3.1M
Inhibition of Oral Tumorigenesis by Antitumor BR01CA205633 · NCI · METHODIST HOSPITAL RESEARCH INSTITUTE · PI HU, MING, WONG, STUART J · 2017 to 2022
$2.6M
NCI NIH HHS R01 CA205633NCI NIH HHS R01 CA208648NCI NIH HHS R01 CA223804
6 · The paper itself

Abstract

Ruan Hua Tang (RHT) and Ruan Hua Fang (RHF) are two Chinese herbal mixtures that have been used in clinical cancer treatment for decades. This study validated our hypothesis that RHT and RHF can inhibit lung tumor development in the mouse model of Benzo(a)pyrene-induced lung tumorigenesis. An RHT oral solution was diluted to 9% and 18% in water. RHF was mixed into the diet at 15% and 30% of total food in the final doses. Two weeks after injecting BP into mice, we administered RHT and RHF for eighteen weeks. We found that 9% and 18% RHT reduced tumor multiplicity by 36.05% and 38.81% (both

Indexed as

A/J micechemopreventionlung cancerRuan Hua FangRuan Hua Tang

Identifiers

PMID38139793
PMCPMC10748223
OpenAlexW4389194467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.