Evidence map›Paper›PMID 38139790›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

Unveiling the Role of Nonionic Surfactants in Enhancing Cefotaxime Drug Solubility: A UV-Visible Spectroscopic Investigation in Single and Mixed Micellar Formulations.

Aysha Arshad Rana, Amnah Yusaf, Salma Shahid, Muhammad Usman, Matloob Ahmad, Sana Aslam, Sami A Al-Hussain, Magdi E A Zaki

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Triazole-imidazo[1,2-International journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Aysha Arshad RanaDepartment of Chemistry, Government College Women University, Faisalabad 38000, Pakistan.
Amnah YusafDepartment of Chemistry, Government College Women University, Faisalabad 38000, Pakistan.ORCID 0000-0002-0812-111X
Salma ShahidDepartment of Biochemistry, Government College Women University, Faisalabad 38000, Pakistan.
Muhammad UsmanDepartment of Chemistry, Government College University, Faisalabad 38000, Pakistan.
Matloob AhmadDepartment of Chemistry, Government College University, Faisalabad 38000, Pakistan.ORCID 0000-0003-1302-8056
Sana AslamDepartment of Chemistry, Government College Women University, Faisalabad 38000, Pakistan.
Sami A Al-HussainDepartment of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11623, Saudi Arabia.
Magdi E A ZakiDepartment of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11623, Saudi Arabia.ORCID 0000-0002-5643-9202
Government College Women University Faisalabad · PKGovernment College University, Faisalabad · PKImam Mohammad ibn Saud Islamic University · SA

Funding

Higher Education Commission HEC-NRPU
6 · The paper itself

Abstract

This study reports the interfacial phenomenon of cefotaxime in combination with nonionic surfactants, Triton X-100 (TX-100) and Tween-80 (TW-80), and their mixed micellar formulations. Cefotaxime was enclosed in a micellar system to improve its solubility and effectiveness. TX-100 and TW-80 were used in an amphiphilic self-assembly process to create the micellar formulation. The effect of the addition of TX-100, a nonionic surfactant, on the ability of TW-80 to solubilize the drug was examined. The values of the critical micelle concentration (CMC) were determined via UV-Visible spectroscopy. Gibbs free energies (ΔG

Indexed as

cefotaximedrug deliveryencapsulation efficiencymixed micellenonionic surfactantspartition coefficientsolubilization

Identifiers

PMID38139790
PMCPMC10747636
OpenAlexW4389203285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.