Evidence map›Paper›PMID 38139438›Full record

ArticleInternational journal of molecular sciences2023

Pathogenic Variants in

Jacques S Fritze, Felizitas F Stiehler, Uwe Wolfrum

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jacques S FritzeInstitute of Molecular Physiology, Johannes Gutenberg University Mainz, 55128 Mainz, Germany.ORCID 0000-0001-8484-8567
Felizitas F StiehlerInstitute of Molecular Physiology, Johannes Gutenberg University Mainz, 55128 Mainz, Germany.ORCID 0009-0003-4105-219X
Uwe WolfrumInstitute of Molecular Physiology, Johannes Gutenberg University Mainz, 55128 Mainz, Germany.ORCID 0000-0002-4756-5872
Johannes Gutenberg University Mainz · DE

Funding

Foundation Fighting Blindness PPA-0717-0719-RAD
6 · The paper itself

Abstract

Pre-mRNA splicing is an essential process orchestrated by the spliceosome, a dynamic complex assembled stepwise on pre-mRNA. We have previously identified that

Indexed as

RNA Splicing FactorsSpliceosomesUsher SyndromesEye ProteinsHEK293 CellsHumansNerve Tissue ProteinsRibonucleoprotein, U4-U6 Small NuclearRNA PrecursorsRNA SplicingTranscription FactorsEye ProteinsNerve Tissue ProteinsPRPF31 protein, humanPRPF6 protein, humanRibonucleoprotein, U4-U6 Small NuclearRNA PrecursorsRNA Splicing FactorsTranscription FactorsUSH1G protein, humanAlphaFold2FRETin silico structure predictionsprotein–protein interactionsplicingU4/U6.U5 tri-snRNPUsher syndrome

Identifiers

PMID38139438
PMCPMC10744108
OpenAlexW4389920738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.