Evidence map›Paper›PMID 38139431›Full record

ArticleInternational journal of molecular sciences2023

DNA Copy Number Alterations and Copy Neutral Loss of Heterozygosity in Adult Ph-Negative Acute B-Lymphoblastic Leukemia: Focus on the Genes Involved.

Natalya Risinskaya, Maria Gladysheva, Abdulpatakh Abdulpatakhov, Yulia Chabaeva, Valeriya Surimova, Olga Aleshina, Anna Yushkova, Olga Dubova, Nikolay Kapranov, Irina Galtseva and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. International journal of molecular sciences · 2025
    Article
  2. International journal of molecular sciences · 2025
    Article
  3. Article
  4. Biallelic Loss of 7q34 (International journal of molecular sciences · 2024
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Natalya RisinskayaNational Medical Research Center for Hematology, 125167 Moscow, Russia.ORCID 0000-0003-2957-1619
Maria GladyshevaNational Medical Research Center for Hematology, 125167 Moscow, Russia.
Abdulpatakh AbdulpatakhovNational Medical Research Center for Hematology, 125167 Moscow, Russia.
Yulia ChabaevaNational Medical Research Center for Hematology, 125167 Moscow, Russia.ORCID 0000-0001-8044-598X
Valeriya SurimovaNational Medical Research Center for Hematology, 125167 Moscow, Russia.ORCID 0009-0004-0323-1493
Olga AleshinaNational Medical Research Center for Hematology, 125167 Moscow, Russia.
Anna YushkovaNational Medical Research Center for Hematology, 125167 Moscow, Russia.
Olga DubovaNational Medical Research Center for Hematology, 125167 Moscow, Russia.
Nikolay KapranovNational Medical Research Center for Hematology, 125167 Moscow, Russia.
Irina GaltsevaNational Medical Research Center for Hematology, 125167 Moscow, Russia.
Sergey KulikovNational Medical Research Center for Hematology, 125167 Moscow, Russia.
Tatiana ObukhovaNational Medical Research Center for Hematology, 125167 Moscow, Russia.ORCID 0000-0003-1613-652X
Andrey SudarikovNational Medical Research Center for Hematology, 125167 Moscow, Russia.ORCID 0000-0001-9463-9187
Elena ParovichnikovaNational Medical Research Center for Hematology, 125167 Moscow, Russia.
National Medical Research Center for Hematology · RUSechenov University · RU

Funding

Russian Science Foundation (RSF) No. 23-25-00490
6 · The paper itself

Abstract

The landscape of chromosomal aberrations in the tumor cells of the patients with B-ALL is diverse and can influence the outcome of the disease. Molecular karyotyping at the onset of the disease using chromosomal microarray (CMA) is advisable to identify additional molecular factors associated with the prognosis of the disease. Molecular karyotyping data for 36 patients with Ph-negative B-ALL who received therapy according to the ALL-2016 protocol are presented. We analyzed copy number alterations and their prognostic significance for

Indexed as

Immediate-Early ProteinsPrecursor Cell Lymphoblastic Leukemia-LymphomaAdultChromosome AberrationsDNADNA Copy Number VariationsGuanine Nucleotide Exchange FactorsHumansLoss of HeterozygosityNuclear ProteinsTumor Suppressor ProteinsBTG2 protein, humanDNADOCK8 protein, humanGuanine Nucleotide Exchange FactorsHEMGN protein, humanImmediate-Early ProteinsNuclear ProteinsTumor Suppressor Proteinsacute B-lymphoblastic leukemia (B-ALL)copy neutral loss of heterozygosity (cnLOH)copy number alterations (CNAs)genesmolecular karyotype

Identifiers

PMID38139431
PMCPMC10744257
OpenAlexW4389884512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.