Evidence map›Paper›PMID 38139358›Full record

ArticleInternational journal of molecular sciences2023

In Vitro and In Vivo Evidence towards Fibronectin's Protective Effects against Prion Infection.

M Carmen Garza, Sang-Gyun Kang, Chiye Kim, Eva Monleón, Jacques van der Merwe, David A Kramer, Richard Fahlman, Valerie L Sim, Judd Aiken, Debbie McKenzie and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

M Carmen GarzaCentre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, AB T6G 2M8, Canada.ORCID 0000-0001-7098-2327
Sang-Gyun KangCentre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, AB T6G 2M8, Canada.
Chiye KimCentre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, AB T6G 2M8, Canada.
Eva MonleónCentro de Encefalopatías y Enfermedades Transmisibles Emergentes, Departamento de Anatomía e Histología Humana, Universidad de Zaragoza, IA2, IIS Aragón, 50013 Zaragoza, Spain.
Jacques van der MerweCentre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, AB T6G 2M8, Canada.
David A KramerDepartment of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB T6G 1C9, Canada.ORCID 0000-0003-2434-3764
Richard FahlmanDepartment of Biochemistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Valerie L SimCentre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, AB T6G 2M8, Canada.ORCID 0000-0002-0088-8666
Judd AikenCentre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, AB T6G 2M8, Canada.
Debbie McKenzieCentre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, AB T6G 2M8, Canada.
Leonardo M CortezCentre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, AB T6G 2M8, Canada.
Holger WilleCentre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, AB T6G 2M8, Canada.ORCID 0000-0001-5102-8706
University of Alberta · CAUniversidad de Zaragoza · ES

Funding

Alberta Prion Research Institute 201300005
6 · The paper itself

Abstract

A distinctive signature of the prion diseases is the accumulation of the pathogenic isoform of the prion protein, PrP

Indexed as

FibronectinsPrion DiseasesPrionsScrapieAnimalsCell LineHumansSheepFibronectinsPrionsextracellular matrix (ECM)k fibronectinmusclemyotubeprionreserve cellsscrapietropism

Identifiers

PMID38139358
PMCPMC10743696
OpenAlexW4389794786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.