Evidence map›Paper›PMID 38139270›Full record

ArticleInternational journal of molecular sciences2023

Maackiain Mimics Caloric Restriction through

Saveta G Mladenova, Monika N Todorova, Martina S Savova, Milen I Georgiev, Liliya V Mihaylova

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Antioxidants (Basel, Switzerland) · 2026
    Article
  2. Phytochemical Profiling and Anti-Obesogenic Potential ofMolecules (Basel, Switzerland) · 2025
    Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Saveta G MladenovaIndependent Researcher, 1000 Sofia, Bulgaria.
Monika N TodorovaLaboratory of Metabolomics, Institute of Microbiology, Bulgarian Academy of Sciences, 139 Ruski Blvd., 4000 Plovdiv, Bulgaria.
Martina S SavovaLaboratory of Metabolomics, Institute of Microbiology, Bulgarian Academy of Sciences, 139 Ruski Blvd., 4000 Plovdiv, Bulgaria.ORCID 0000-0002-3852-8658
Milen I GeorgievLaboratory of Metabolomics, Institute of Microbiology, Bulgarian Academy of Sciences, 139 Ruski Blvd., 4000 Plovdiv, Bulgaria.ORCID 0000-0001-5248-6135
Liliya V MihaylovaLaboratory of Metabolomics, Institute of Microbiology, Bulgarian Academy of Sciences, 139 Ruski Blvd., 4000 Plovdiv, Bulgaria.ORCID 0000-0002-1690-1490
Bulgarian Academy of Sciences · BG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity prevalence is becoming a serious global health and economic issue and is a major risk factor for concomitant diseases that worsen the quality and duration of life. Therefore, the urgency of the development of novel therapies is of a particular importance. A previous study of ours revealed that the natural pterocarpan, maackiain (MACK), significantly inhibits adipogenic differentiation in human adipocytes through a peroxisome proliferator-activated receptor gamma (PPARγ)-dependent mechanism. Considering the observed anti-adipogenic potential of MACK, we aimed to further elucidate the molecular mechanisms that drive its biological activity in a

Indexed as

Caenorhabditis elegans ProteinsPterocarpansAMP-Activated Protein KinasesAnimalsCaenorhabditis elegansCaloric RestrictionHumansLipidsMammalsObesityPhytoalexinsAMP-Activated Protein KinasesCaenorhabditis elegans ProteinsinerminLipidsPhytoalexinsPterocarpansAMPKCaenorhabditis eleganslipid accumulationmaackiainobesityorlistat

Identifiers

PMID38139270
PMCPMC10744277
OpenAlexW4389685729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.