Evidence map›Paper›PMID 38139134›Full record

ReviewInternational journal of molecular sciences2023

Vitiligo: Pathogenesis and New and Emerging Treatments.

Javier Perez-Bootello, Ruth Cova-Martin, Jorge Naharro-Rodriguez, Gonzalo Segurado-Miravalles

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

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  16. Observational
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  19. Frontiers in pharmacology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Javier Perez-BootelloRamon y Cajal University Hospital, Road M-607, 9, 100, 28034 Madrid, Spain.ORCID 0009-0009-2253-5587
Ruth Cova-MartinRamon y Cajal University Hospital, Road M-607, 9, 100, 28034 Madrid, Spain.
Jorge Naharro-RodriguezRamon y Cajal University Hospital, Road M-607, 9, 100, 28034 Madrid, Spain.ORCID 0000-0002-0136-9032
Gonzalo Segurado-MiravallesRamon y Cajal University Hospital, Road M-607, 9, 100, 28034 Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitiligo is a complex disease with a multifactorial nature and a high impact on the quality of life of patients. Although there are multiple therapeutic alternatives, there is currently no fully effective treatment for this disease. In the current era, multiple drugs are being developed for the treatment of autoimmune diseases. This review assesses the available evidence on the pathogenesis of vitiligo, and a comprehensive review of treatments available for vitiligo now and in the near future is provided. This qualitative analysis spans 116 articles. We reviewed the mechanism of action, efficacy and safety data of phototherapy, afamelanotide, cyclosporine, phosphodiesterase 4 inhibitors, trichloroacetic acid, basic fibroblast growth factor, tumor necrosis factor (TNF) inhibitors, secukinumab, pseudocatalase and janus kinase (JAK) inhibitors. At the moment, there is no clearly outstanding option or fully satisfactory treatment for vitiligo, so it is necessary to keep up the development of new drugs as well as the publication of long-term effectiveness and safety data for existing treatments.

Indexed as

Janus Kinase InhibitorsVitiligoHumansPhototherapyQuality of LifeTreatment OutcomeJanus Kinase InhibitorsJAK inhibitorpathogenesistherapeuticsvitiligo

Identifiers

PMID38139134
PMCPMC10743634

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.