Evidence map›Paper›PMID 38139132›Full record

ReviewInternational journal of molecular sciences2023

The Implication of Sphingolipids in Viral Infections.

Sanya Thomas, Stephen Varghese Samuel, Annmarie Hoch, Caitlin Syphurs, Joann Diray-Arce

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Local host fish-Food and waterborne parasitology · 2026
    Article
  4. Network Pharmacology-Guided Identification ofInternational journal of molecular sciences · 2026
    Article
  5. Measles virus reprograms CD4Frontiers in cell and developmental biology · 2026
    Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Sanya ThomasPrecision Vaccines Program, Department of Pediatrics, Boston Children's Hospital, Boston, MA 02115, USA.ORCID 0000-0003-3648-9461
Stephen Varghese SamuelHarvard Medical School, Boston, MA 02115, USA.ORCID 0000-0002-3123-2029
Annmarie HochPrecision Vaccines Program, Department of Pediatrics, Boston Children's Hospital, Boston, MA 02115, USA.ORCID 0000-0003-0836-2164
Caitlin SyphursPrecision Vaccines Program, Department of Pediatrics, Boston Children's Hospital, Boston, MA 02115, USA.
Joann Diray-ArcePrecision Vaccines Program, Department of Pediatrics, Boston Children's Hospital, Boston, MA 02115, USA.ORCID 0000-0003-2183-4269
Boston Children's Hospital · USHarvard University · US

Funding

Transcriptomics to define biomarkers of neonatal vaccine immunogenicityU19AI118608 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI LEVY, OFER · 2017 to 2021
$24.7M
Proteomics and Metabolomics Core: IDEAL shapes vaccine response, susceptibility to respiratory infectious disease and asthmaU19AI168643 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI OFER LEVY · 2022 to 2026
$10.0M
NIAID NIH HHS U19 AI118608NIAID NIH HHS U19 AI168643
6 · The paper itself

Abstract

Sphingolipids are involved in cell signaling and metabolic pathways, and their metabolites play a critical role in host defense against intracellular pathogens. Here, we review the known mechanisms of sphingolipids in viral infections and discuss the potential implication of the study of sphingolipid metabolism in vaccine and therapeutic development.

Indexed as

SphingolipidsVirus DiseasesHumansLipid MetabolismMetabolic Networks and PathwaysSignal TransductionSphingosineSphingolipidsSphingosinelipid metabolismsphingolipid metabolismsphingolipidssphingosine-1-phosphateviral infections

Identifiers

PMID38139132
PMCPMC10743733
OpenAlexW4389566286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.