Evidence map›Paper›PMID 38139096›Full record

ArticleInternational journal of molecular sciences2023

Investigating the Human Intestinal DNA Virome and Predicting Disease-Associated Virus-Host Interactions in Severe Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).

Shen-Yuan Hsieh, George M Savva, Andrea Telatin, Sumeet K Tiwari, Mohammad A Tariq, Fiona Newberry, Katharine A Seton, Catherine Booth, Amolak S Bansal, Thomas Wileman and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Shen-Yuan HsiehFood, Microbiome, and Health Research Programme, Quadram Institute Bioscience, Norwich Research Park, Norwich NR4 7UQ, UK.ORCID 0000-0003-2244-1491
George M SavvaCore Science Resources, Quadram Institute Bioscience, Norwich NR4 7UQ, UK.
Andrea TelatinFood, Microbiome, and Health Research Programme, Quadram Institute Bioscience, Norwich Research Park, Norwich NR4 7UQ, UK.ORCID 0000-0001-7619-281X
Sumeet K TiwariFood, Microbiome, and Health Research Programme, Quadram Institute Bioscience, Norwich Research Park, Norwich NR4 7UQ, UK.
Mohammad A TariqFood, Microbiome, and Health Research Programme, Quadram Institute Bioscience, Norwich Research Park, Norwich NR4 7UQ, UK.ORCID 0000-0002-2424-5323
Fiona NewberryFood, Microbiome, and Health Research Programme, Quadram Institute Bioscience, Norwich Research Park, Norwich NR4 7UQ, UK.
Katharine A SetonFood, Microbiome, and Health Research Programme, Quadram Institute Bioscience, Norwich Research Park, Norwich NR4 7UQ, UK.ORCID 0000-0002-5657-296X
Catherine BoothCore Science Resources, Quadram Institute Bioscience, Norwich NR4 7UQ, UK.ORCID 0000-0001-9435-6937
Amolak S BansalSpire St. Anthony's Hospital, Surrey SM3 9DW, UK.
Thomas WilemanFood, Microbiome, and Health Research Programme, Quadram Institute Bioscience, Norwich Research Park, Norwich NR4 7UQ, UK.ORCID 0000-0002-9033-2580
Evelien M AdriaenssensFood, Microbiome, and Health Research Programme, Quadram Institute Bioscience, Norwich Research Park, Norwich NR4 7UQ, UK.ORCID 0000-0003-4826-5406
Simon R CardingFood, Microbiome, and Health Research Programme, Quadram Institute Bioscience, Norwich Research Park, Norwich NR4 7UQ, UK.ORCID 0000-0002-2383-9701
Norwich Research Park · GBQuadram Institute · GBUniversity of East Anglia · GBSpire St Anthony’s Hospital · GB

Funding

Biotechnology and Biological Sciences Research Council BBS/E/F/000PR10355Biotechnology and Biological Sciences Research Council BBS/E/F/000PR10356Biotechnology and Biological Sciences Research Council BB/X011054/1
6 · The paper itself

Abstract

Understanding how the human virome, and which of its constituents, contributes to health or disease states is reliant on obtaining comprehensive virome profiles. By combining DNA viromes from isolated virus-like particles (VLPs) and whole metagenomes from the same faecal sample of a small cohort of healthy individuals and patients with severe myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), we have obtained a more inclusive profile of the human intestinal DNA virome. Key features are the identification of a core virome comprising tailed phages of the class

Indexed as

Fatigue Syndrome, ChronicDNAHost Microbial InteractionsHumansViromeDNAbacteriomebacteriophagemyalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)viral operational taxonomic unit (vOTU)viromevirus-like particle (VLP)

Identifiers

PMID38139096
PMCPMC10744171
OpenAlexW4389488642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.