Evidence map›Paper›PMID 38139095›Full record

ArticleInternational journal of molecular sciences2023

Amphiphilic Sialic Acid Derivatives as Potential Dual-Specific Inhibitors of Influenza Hemagglutinin and Neuraminidase.

Eszter Boglárka Lőrincz, Mihály Herczeg, Josef Houser, Martina Rievajová, Ákos Kuki, Lenka Malinovská, Lieve Naesens, Michaela Wimmerová, Anikó Borbás, Pál Herczegh and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Eszter Boglárka LőrinczDepartment of Pharmaceutical Chemistry, University of Debrecen, H-4032 Debrecen, Hungary.
Mihály HerczegDepartment of Pharmaceutical Chemistry, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0002-7938-9789
Josef HouserNational Centre for Biomolecular Research, Masaryk University, 611 37 Brno, Czech Republic.ORCID 0000-0003-4504-3891
Martina RievajováDepartment of Biochemistry, Faculty of Science, Masaryk University, 611 37 Brno, Czech Republic.
Ákos KukiDepartment of Applied Chemistry, University of Debrecen, H-4032 Debrecen, Hungary.
Lenka MalinovskáNational Centre for Biomolecular Research, Masaryk University, 611 37 Brno, Czech Republic.
Lieve NaesensRega Institute for Medical Research, KU Leuven, B-3000 Leuven, Belgium.ORCID 0000-0001-9742-9302
Michaela WimmerováNational Centre for Biomolecular Research, Masaryk University, 611 37 Brno, Czech Republic.ORCID 0000-0002-7108-4198
Anikó BorbásDepartment of Pharmaceutical Chemistry, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0001-8462-4547
Pál HerczeghDepartment of Pharmaceutical Chemistry, University of Debrecen, H-4032 Debrecen, Hungary.
Ilona BereczkiDepartment of Pharmaceutical Chemistry, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0003-4601-7257

Funding

European Regional Development Fund-Project CZ.02.1.01/0.0/0.0/18_046/0015974MEYS CR LM2023042National Laboratory of Virology in Hungary RRF-2.3.1-21-2022-00010National Research, Development and Innovation Office FK 142315
6 · The paper itself

Abstract

In the shadow of SARS-CoV-2, influenza seems to be an innocent virus, although new zoonotic influenza viruses evolved by mutations may lead to severe pandemics. According to WHO, there is an urgent need for better antiviral drugs. Blocking viral hemagglutinin with multivalent

Indexed as

Influenza A Virus, H1N1 SubtypeInfluenza, HumanHemagglutinin Glycoproteins, Influenza VirusHemagglutininsHumansInfluenza A Virus, H3N2 SubtypeN-Acetylneuraminic AcidNeuraminic AcidsNeuraminidaseHemagglutinin Glycoproteins, Influenza VirusHemagglutininsN-Acetylneuraminic AcidNeuraminic AcidsNeuraminidaseaggregateshemagglutinininfluenzaneuraminidasesialic acid

Identifiers

PMID38139095
PMCPMC10743929

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.