Evidence map›Paper›PMID 38139040›Full record

ArticleInternational journal of molecular sciences2023

Metabolomics (Non-Targeted) of Induced Type 2 Diabetic Sprague Dawley Rats Comorbid with a Tissue-Dwelling Nematode Parasite.

Innocent Siyanda Ndlovu, Selaelo Ivy Tshilwane, Philile Ignecious Ngcamphalala, Andre' Vosloo, Mamohale Chaisi, Samson Mukaratirwa

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Innocent Siyanda NdlovuSchool of Life Sciences, University of KwaZulu-Natal, Westville Campus, Durban 4001, South Africa.ORCID 0000-0002-1384-2026
Selaelo Ivy TshilwaneDepartment of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Pretoria 0110, South Africa.ORCID 0000-0002-3549-4675
Philile Ignecious NgcamphalalaSchool of Life Sciences, University of KwaZulu-Natal, Westville Campus, Durban 4001, South Africa.
Andre' VoslooSchool of Life Sciences, University of KwaZulu-Natal, Westville Campus, Durban 4001, South Africa.
Mamohale ChaisiDepartment of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Pretoria 0110, South Africa.
Samson MukaratirwaSchool of Life Sciences, University of KwaZulu-Natal, Westville Campus, Durban 4001, South Africa.ORCID 0000-0001-6843-1497
University of KwaZulu-Natal · ZARoss University School of Veterinary Medicine · KNSouth African National Biodiversity Institute · ZAUniversity of Pretoria · ZA

Funding

National Research Foundation: Professional Development Programme (PDP) P2020/11Ross University School of Veterinary Medicine 41011-20
6 · The paper itself

Abstract

Type 2 diabetes is a non-communicable metabolic syndrome that is characterized by the dysfunction of pancreatic β-cells and insulin resistance. Both animal and human studies have been conducted, demonstrating that helminth infections are associated with a decreased prevalence of type 2 diabetes mellitus (T2DM). However, there is a paucity of information on the impact that helminths have on the metabolome of the host and how the infection ameliorates T2DM or its progression. Therefore, this study aimed at using a non-targeted metabolomics approach to systematically identify differentiating metabolites from serum samples of T2DM-induced Sprague Dawley (SD) rats infected with a tissue-dwelling nematode,

Indexed as

Diabetes Mellitus, Type 2Metabolic SyndromeParasitesTrichinellaAnimalsComorbidityHumansMaleMetabolomicsRatsRats, Sprague-Dawleyamino acidscarbohydratesmetabolomicsSprague Dawley ratsTrichinella zimbabwensistype 2 diabetes

Identifiers

PMID38139040
PMCPMC10743009
OpenAlexW4389451989

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.