Evidence map›Paper›PMID 38138927›Full record

ArticleJournal of personalized medicine2023

Evaluation of the Acid-Base Status in Patients Admitted to the ICU Due to Severe COVID-19: Physicochemical versus Traditional Approaches.

Zoi Sotiropoulou, Elvira Markela Antonogiannaki, Evangelia Koukaki, Stavroula Zaneli, Agamemnon Bakakos, Angelos Vontetsianos, Nektarios Anagnostopoulos, Nikoleta Rovina, Konstantinos Loverdos, Paraskevi Tripolitsioti and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Predictive Value of Anion Gap for Acute Kidney Injury Progression and Outcomes.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Zoi Sotiropoulou1st Department of Respiratory Medicine, National and Kapodistrian University of Athens, School of Medicine, Sotiria Chest Hospital, Mesogeion 152, 11527 Athens, Greece.
Elvira Markela Antonogiannaki4th Department of Respiratory Medicine, Sotiria Chest Hospital, 11527 Athens, Greece.ORCID 0009-0002-5467-5225
Evangelia Koukaki1st Department of Respiratory Medicine, National and Kapodistrian University of Athens, School of Medicine, Sotiria Chest Hospital, Mesogeion 152, 11527 Athens, Greece.ORCID 0000-0002-9770-173X
Stavroula Zaneli1st Department of Respiratory Medicine, National and Kapodistrian University of Athens, School of Medicine, Sotiria Chest Hospital, Mesogeion 152, 11527 Athens, Greece.
Agamemnon Bakakos1st Department of Respiratory Medicine, National and Kapodistrian University of Athens, School of Medicine, Sotiria Chest Hospital, Mesogeion 152, 11527 Athens, Greece.ORCID 0000-0001-8933-6800
Angelos Vontetsianos1st Department of Respiratory Medicine, National and Kapodistrian University of Athens, School of Medicine, Sotiria Chest Hospital, Mesogeion 152, 11527 Athens, Greece.ORCID 0009-0009-5794-3089
Nektarios Anagnostopoulos1st Department of Respiratory Medicine, National and Kapodistrian University of Athens, School of Medicine, Sotiria Chest Hospital, Mesogeion 152, 11527 Athens, Greece.ORCID 0000-0003-4925-2332
Nikoleta Rovina1st Department of Respiratory Medicine, National and Kapodistrian University of Athens, School of Medicine, Sotiria Chest Hospital, Mesogeion 152, 11527 Athens, Greece.ORCID 0000-0003-0138-5582
Konstantinos Loverdos1st Department of Respiratory Medicine, National and Kapodistrian University of Athens, School of Medicine, Sotiria Chest Hospital, Mesogeion 152, 11527 Athens, Greece.
Paraskevi Tripolitsioti1st Department of Respiratory Medicine, National and Kapodistrian University of Athens, School of Medicine, Sotiria Chest Hospital, Mesogeion 152, 11527 Athens, Greece.
Magdalini Kyriakopoulou1st Department of Respiratory Medicine, National and Kapodistrian University of Athens, School of Medicine, Sotiria Chest Hospital, Mesogeion 152, 11527 Athens, Greece.
Konstantinos Pontikis1st Department of Respiratory Medicine, National and Kapodistrian University of Athens, School of Medicine, Sotiria Chest Hospital, Mesogeion 152, 11527 Athens, Greece.ORCID 0000-0002-3533-9608
Petros Bakakos1st Department of Respiratory Medicine, National and Kapodistrian University of Athens, School of Medicine, Sotiria Chest Hospital, Mesogeion 152, 11527 Athens, Greece.ORCID 0000-0001-9256-9656
Dimitrios GeorgopoulosIntensive Care Medicine Department, University Hospital of Heraklion, Medical School, University of Crete, 71110 Heraklion, Greece.ORCID 0000-0003-3689-9014
Andriana I Papaioannou1st Department of Respiratory Medicine, National and Kapodistrian University of Athens, School of Medicine, Sotiria Chest Hospital, Mesogeion 152, 11527 Athens, Greece.ORCID 0000-0001-9708-3241

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStewart's approach is known to have better diagnostic accuracy for the identification of metabolic acid-base disturbances compared to traditional methods based either on plasma bicarbonate concentration ([HCO

methodsThis was a single-center retrospective study, in which we collected data from patients with severe COVID-19 admitted to the ICU. Electronical files were used to retrieve data for arterial blood gases, serum electrolytes, and proteins and to derive [HCO

resultsWe included 185 patients. The physicochemical approach detected more individuals with metabolic acid-base abnormalities than the BE and [HCO

conclusionsThe identification of hidden acid-base disturbances may provide a detailed understanding of the underlying conditions in patients and of the possible pathophysiological mechanisms implicated. The association of these acid-base abnormalities with mortality provides the opportunity to recognize patients at increased risk of death and support them accordingly.

Indexed as

acid–base disordersbase excessCOVID-19intensive care unitphysicochemical approach

Identifiers

PMID38138927
PMCPMC10744463

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.