Evidence map›Paper›PMID 38138880›Full record

ArticleJournal of personalized medicine2023

Desmoid Tumors in the Active Surveillance Era: Evaluation of Treatment Options and Pain Relief in a Single-Center Retrospective Analysis.

Marco Rastrelli, Benedetta Chiusole, Francesco Cavallin, Paolo Del Fiore, Andrea Angelini, Maria Chiara Cerchiaro, Pietro Ruggieri, Marta Sbaraglia, Simone Mocellin, Antonella Brunello

Abstract read
In one paragraph

Article in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marco RastrelliSoft-Tissue, Peritoneum and Melanoma Surgical Oncology Unit, Veneto Institute of Oncology IOV-IRCCS, 35128 Padua, Italy.
Benedetta ChiusoleOncology 1, Department of Oncology, Veneto Institute of Oncology IOV-IRCCS, 35128 Padua, Italy.ORCID 0000-0001-6449-6402
Francesco CavallinIndependent Statistician, 36020 Solagna, Italy.ORCID 0000-0002-0831-3971
Paolo Del FioreSoft-Tissue, Peritoneum and Melanoma Surgical Oncology Unit, Veneto Institute of Oncology IOV-IRCCS, 35128 Padua, Italy.ORCID 0000-0002-2862-8014
Andrea AngeliniDepartment of Orthopedics and Orthopedic Oncology, University of Padova, 35128 Padua, Italy.ORCID 0000-0002-8823-448X
Maria Chiara CerchiaroDepartment of Orthopedics and Orthopedic Oncology, University of Padova, 35128 Padua, Italy.
Pietro RuggieriDepartment of Orthopedics and Orthopedic Oncology, University of Padova, 35128 Padua, Italy.ORCID 0000-0001-9617-9882
Marta SbaragliaDepartment of Medicine (DIMED), University of Padua School of Medicine, 35128 Padua, Italy.
Simone MocellinSoft-Tissue, Peritoneum and Melanoma Surgical Oncology Unit, Veneto Institute of Oncology IOV-IRCCS, 35128 Padua, Italy.
Antonella BrunelloOncology 1, Department of Oncology, Veneto Institute of Oncology IOV-IRCCS, 35128 Padua, Italy.ORCID 0000-0003-2583-5226

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In patients with desmoid tumors (DTs), active surveillance has been increasingly preferred over surgery, while treatment (including pharmacological therapy, radiotherapy, and/or surgery) is performed in cases with confirmed disease progression. This study aimed to evaluate event-free survival and pain management according to different treatment strategies. We evaluated event-free survival, including recurrence after initial surgical treatment or changes in the therapeutic management after initial non-surgical treatment and pain management according to different treatment strategies. All patients referred for DT in 2001-2021 at our institutions were stratified into four groups: those treated surgically prior to 2012 (SGPre12) or after 2012 (SGPost12), those treated pharmacologically (MG), and those under active surveillance (ASG). An event was defined as recurrence after initial surgical treatment or a change in therapeutic management. Overall, 123 patients were included in the study: 28 in SGPre12, 41 in SGPost12, 38 in MG, and 16 in ASG. Pharmacological treatment resolved painful symptoms in 16/27 (60%) patients (

Indexed as

active surveillancedesmoid tumortherapeutic management

Identifiers

PMID38138880
PMCPMC10744644

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.