Evidence map›Paper›PMID 38138621›Full record

ReviewMolecules (Basel, Switzerland)2023

Mediterranean Shrub Species as a Source of Biomolecules against Neurodegenerative Diseases.

Natividad Chaves, Laura Nogales, Ismael Montero-Fernández, José Blanco-Salas, Juan Carlos Alías

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Natividad ChavesDepartment of Plant Biology, Ecology and Earth Sciences, Faculty of Science, Universidad de Extremadura, 06080 Badajoz, Spain.ORCID 0000-0003-0096-9658
Laura NogalesDepartment of Plant Biology, Ecology and Earth Sciences, Faculty of Science, Universidad de Extremadura, 06080 Badajoz, Spain.
Ismael Montero-FernándezDepartment of Plant Biology, Ecology and Earth Sciences, Faculty of Science, Universidad de Extremadura, 06080 Badajoz, Spain.ORCID 0000-0003-4438-9372
José Blanco-SalasDepartment of Plant Biology, Ecology and Earth Sciences, Faculty of Science, Universidad de Extremadura, 06080 Badajoz, Spain.ORCID 0000-0001-6525-4448
Juan Carlos AlíasDepartment of Plant Biology, Ecology and Earth Sciences, Faculty of Science, Universidad de Extremadura, 06080 Badajoz, Spain.ORCID 0000-0001-8137-0369
Universidad de Extremadura · ES

Funding

Ministry of Economy, Science and Digital Agenda of the Government of Extremadura and by the European Regional Development Fund (FEDER) of Extremadura LA4:Evaluation and mitigation of the impact of global change on biodiversity - FEDER Funds" / LIA4 Complementary Plan
6 · The paper itself

Abstract

Neurodegenerative diseases are associated with oxidative stress, due to an imbalance in the oxidation-reduction reactions at the cellular level. Various treatments are available to treat these diseases, although they often do not cure them and have many adverse effects. Therefore, it is necessary to find complementary and/or alternative drugs that replace current treatments with fewer side effects. It has been demonstrated that natural products derived from plants, specifically phenolic compounds, have a great capacity to suppress oxidative stress and neutralize free radicals thus, they may be used as alternative alternative pharmacological treatments for pathological conditions associated with an increase in oxidative stress. The plant species that dominate the Mediterranean ecosystems are characterized by having a wide variety of phenolic compound content. Therefore, these species might be important sources of neuroprotective biomolecules. To evaluate this potential, 24 typical plant species of the Mediterranean ecosystems were selected, identifying the most important compounds present in them. This set of plant species provides a total of 403 different compounds. Of these compounds, 35.7% are phenolic acids and 55.6% are flavonoids. The most relevant of these compounds are gallic, vanillic, caffeic, chlorogenic,

Indexed as

CatechinNeurodegenerative DiseasesAntioxidantsEcosystemHumansPhenolsPlant ExtractsAntioxidantsCatechinPhenolsPlant ExtractsMediterranean speciesnatural antioxidantsneuroprotective compoundsphenols

Identifiers

PMID38138621
PMCPMC10745362
OpenAlexW4389917550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.