Evidence map›Paper›PMID 38138600›Full record

ArticleMolecules (Basel, Switzerland)2023

A Robust and Efficient FRET-Based Assay for Cannabinoid Receptor Ligands Discovery.

Gemma Navarro, Eddy Sotelo, Iu Raïch, María Isabel Loza, Jose Brea, Maria Majellaro

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gemma NavarroDepartment of Biochemistry and Physiology, Faculty of Pharmacy and Food Science, University of Barcelona, 08028 Barcelona, Spain.ORCID 0000-0003-4654-0873
Eddy SoteloDepartment of Organic Chemistry, Center for Research in Biological Chemistry and Molecular Materials (CiQUS), University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0001-5571-2812
Iu RaïchDepartment of Biochemistry and Physiology, Faculty of Pharmacy and Food Science, University of Barcelona, 08028 Barcelona, Spain.ORCID 0000-0001-6271-0495
María Isabel LozaResearch Center in Molecular Medicine and Chronic Diseases (CIMUS), University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Jose BreaResearch Center in Molecular Medicine and Chronic Diseases (CIMUS), University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0002-5523-1979
Maria MajellaroCeltarys Research SL, Avda. Mestre Mateo, 2, 15706 Santiago de Compostela, Spain.ORCID 0000-0003-3490-7703

Funding

the Consellería de Cultura, Educación e Ordenación Universitaria of the Galician Government D431B 2020/43the European Regional Development Fund (ERDF). N/AXunta de Galicia PID2020-113430RB-I00
6 · The paper itself

Abstract

The identification of new modulators for Cannabinoid Receptors (CBRs) has garnered significant attention in drug discovery over recent years, owing to their manifold pathophysiological implications. In the context of hit identification, the availability of robust and sensitive high-throughput screening assays is essential to enhance the likelihood of success. In this study, we present the development and validation of a Tag-lite

Indexed as

Drug DiscoveryFluorescence Resonance Energy TransferColoring AgentsLigandsProtein BindingReceptors, CannabinoidColoring AgentsLigandsReceptors, CannabinoidbindingCB1RCB2RHTRFHTS

Identifiers

PMID38138600
PMCPMC10745346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.