Evidence map›Paper›PMID 38138445›Full record

ArticleMolecules (Basel, Switzerland)2023

Palmatine Protects PC12 Cells and Mice from Aβ25-35-Induced Oxidative Stress and Neuroinflammation via the Nrf2/HO-1 Pathway.

Yu Wang, Hongyan Pei, Weijia Chen, Rui Du, Jianming Li, Zhongmei He

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yu WangCollege of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
Hongyan PeiCollege of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
Weijia ChenCollege of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
Rui DuCollege of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
Jianming LiCollege of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
Zhongmei HeCollege of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.ORCID 0000-0002-2694-6510
Jilin Agricultural University · CN

Funding

Jilin Province aid Project for Xinjiang Uygur Autonomous Region 0207-202020043Jilin Province major science and technology special project 20220304002YYJilin Science and Technology Development Program Project 20210204001YY
6 · The paper itself

Abstract

Alzheimer's disease is a common degenerative disease which has a great impact on people's daily lives, but there is still a certain market gap in the drug research about it. Palmatine, one of the main components of Huangteng, the rattan stem of

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAnimalsBerberine AlkaloidsHumansMiceNeuroinflammatory DiseasesNF-E2-Related Factor 2Oxidative StressPC12 CellsPeptide FragmentsRatsReactive Oxygen SpeciesAmyloid beta-Peptidesamyloid beta-protein (25-35)Berberine AlkaloidsNF-E2-Related Factor 2palmatinePeptide FragmentsReactive Oxygen SpeciesAβ25-35-induced Alzheimer’s diseaseneuroinflammationNrf2/HO-1 pathwayoxidative stresspalmatine

Identifiers

PMID38138445
PMCPMC10745955
OpenAlexW4389362744

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.