Evidence map›Paper›PMID 38138101›Full record

ArticleMicroorganisms2023

Oral Microbial Profile Analysis in Patients with Oral and Pharyngeal Cancer Reveals That Tumoral

Yuki Yamamoto, Tomonori Kamiya, Megumu Yano, Vu Thuong Huyen, Masahiro Oishi, Miki Nishio, Akira Suzuki, Kishiko Sunami, Naoko Ohtani

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Functional Heterogeneity ofMicroorganisms · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Yuki YamamotoDepartment of Otolaryngology and Head & Neck Surgery, Graduate School of Medicine, Osaka Metropolitan University, Osaka 545-8585, Japan.
Tomonori KamiyaDepartment of Pathophysiology, Graduate School of Medicine, Osaka Metropolitan University, Osaka 545-8585, Japan.
Megumu YanoDepartment of Pathophysiology, Graduate School of Medicine, Osaka Metropolitan University, Osaka 545-8585, Japan.
Vu Thuong HuyenDepartment of Pathophysiology, Graduate School of Medicine, Osaka Metropolitan University, Osaka 545-8585, Japan.
Masahiro OishiDepartment of Otolaryngology and Head & Neck Surgery, Graduate School of Medicine, Osaka Metropolitan University, Osaka 545-8585, Japan.
Miki NishioDivision of Molecular and Cellular Biology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.
Akira SuzukiDivision of Molecular and Cellular Biology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.
Kishiko SunamiDepartment of Otolaryngology and Head & Neck Surgery, Graduate School of Medicine, Osaka Metropolitan University, Osaka 545-8585, Japan.
Naoko OhtaniDepartment of Pathophysiology, Graduate School of Medicine, Osaka Metropolitan University, Osaka 545-8585, Japan.ORCID 0000-0001-8934-0797
Osaka Metropolitan University · JPKobe University · JPOsaka City University · JPJapan Agency for Medical Research and Development · JP

Funding

Danone Institute of Japan Foundation Danone Institute of Japan Foundation (T. K.)Glocal Hub of Wisdom and Wellness Grant in Osaka City University Glocal Hub of Wisdom and Wellness Grant (K. S.)Japan Agency for Medical Research and Development JP22ama221117Japan Agency for Medical Research and Development JP22gm1010009Japan Society for the Promotion of Science 20K16121Japan Society for the Promotion of Science 21H04806Japan Society for the Promotion of Science 22H03540Takeda Science Foundation Visionary Research (N. O.)Yakult Bio-Science Foundation Yakult Bio-Science Foundation (T. K.)
6 · The paper itself

Abstract

The incidence of oral cancer has recently been increasing worldwide, particularly among young individuals and women. The primary risk factors for head and neck cancers, including oral and pharyngeal cancers, are smoking, alcohol consumption, poor oral hygiene, and repeated exposure to mechanical stimuli. However, approximately one-third of the patients with oral and pharyngeal cancers are neither smokers nor drinkers, which points to the existence of other mechanisms. Recently, human microbes have been linked to various diseases, including cancer. Oral pathogens, especially periodontal pathobionts, are reported to play a role in the development of colon and other types of cancer. In this study, we employed a series of bioinformatics analyses to pinpoint

Indexed as

Fusobacterium nucleatumoral and pharyngeal canceroral microbiomeYes-associated protein (YAP)

Identifiers

PMID38138101
PMCPMC10746018
OpenAlexW4389572565

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.