Evidence map›Paper›PMID 38137955›Full record

ArticleLife (Basel, Switzerland)2023

SARS-CoV-2 in Animal Companions: A Serosurvey in Three Regions of Southern Italy.

Angelica Bianco, Alessio Bortolami, Angela Miccolupo, Roldano Sottili, Paola Ghergo, Stefano Castellana, Laura Del Sambro, Loredana Capozzi, Matteo Pagliari, Francesco Bonfante and 4 more

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Angelica BiancoIstituto Zooprofilattico Sperimentale della Puglia e Basilicata, Via Manfredonia n. 20, 71121 Foggia, Italy.
Alessio BortolamiDepartment of Comparative Biomedical Sciences, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell'Università 10, 35020 Legnaro, Italy.ORCID 0000-0003-3381-8354
Angela MiccolupoIstituto Zooprofilattico Sperimentale della Puglia e Basilicata, Via Manfredonia n. 20, 71121 Foggia, Italy.
Roldano SottiliACV Triggiano Laboratorio di Analisi Cliniche Veterinarie, Via Suor Marcella Arosio 8, 70019 Triggiano, Italy.
Paola GhergoACV Triggiano Laboratorio di Analisi Cliniche Veterinarie, Via Suor Marcella Arosio 8, 70019 Triggiano, Italy.
Stefano CastellanaIstituto Zooprofilattico Sperimentale della Puglia e Basilicata, Via Manfredonia n. 20, 71121 Foggia, Italy.ORCID 0000-0001-8688-9530
Laura Del SambroIstituto Zooprofilattico Sperimentale della Puglia e Basilicata, Via Manfredonia n. 20, 71121 Foggia, Italy.
Loredana CapozziIstituto Zooprofilattico Sperimentale della Puglia e Basilicata, Via Manfredonia n. 20, 71121 Foggia, Italy.
Matteo PagliariDepartment of Comparative Biomedical Sciences, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell'Università 10, 35020 Legnaro, Italy.ORCID 0000-0003-0199-5647
Francesco BonfanteDepartment of Comparative Biomedical Sciences, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell'Università 10, 35020 Legnaro, Italy.ORCID 0000-0002-1276-2710
Donato RidolfiIstituto Zooprofilattico Sperimentale della Puglia e Basilicata, Via Manfredonia n. 20, 71121 Foggia, Italy.
Carmela BulzacchelliIstituto Zooprofilattico Sperimentale della Puglia e Basilicata, Via Manfredonia n. 20, 71121 Foggia, Italy.
Anna GiannicoIstituto Zooprofilattico Sperimentale della Puglia e Basilicata, Via Manfredonia n. 20, 71121 Foggia, Italy.
Antonio ParisiIstituto Zooprofilattico Sperimentale della Puglia e Basilicata, Via Manfredonia n. 20, 71121 Foggia, Italy.

Funding

Italian Ministry of Health RICERCA CORRENTE IZSVE 01/20 RCS AND BY THE EUROPEAN ICRAD MUSECOV (MULTI-SCALE ECO-EVOLUTION OF CORONAVIRUSES: FROM SURVEILLANCE TOWARD EMERGENCE PREDICTION) PROJECT
6 · The paper itself

Abstract

Several animal species have been found to be susceptible to SARS-CoV-2 infection. The occurrence of infection in dogs and cats living in close contact with owners deserves particular attention from public health authorities in a One Health approach. In this study, we conducted serological screening to identify SARS-CoV-2 exposure in the sera from dogs and cats in three regions of southern Italy sampled during the years 2021 and 2022. We collected 100 serum samples in 2021 (89 from dogs and 11 from cats) and 640 in 2022 (577 from dogs and 63 from cats). Overall, the ELISA positivity rate was found to be 2.7% (20/740), with higher seroprevalence in dogs. Serum neutralization tests confirmed positivity only in two samples collected from dogs, and the assays, performed with serologically distinct SARS-CoV-2 variants, showed variant-specific positivity. This paper shows that monitoring SARS-CoV-2 exposure in animals might be affected by the viral antigenic evolution, which requires continuous updates to the serological tests used. Serological surveys are useful in understanding the true extent of exposure occurring in specific animal populations, not suffering the same limitations as molecular tests, and could help in identifying the infecting virus if tests able to characterize the immune response are used. The use of variant-specific validated serological methods should always be considered in serosurvey studies in order to determine the real impact of emerging variants on animal populations and its implications for veterinary and human health, as well as to identify potential reservoirs of the virus and its evolutionary changes.

Indexed as

animalsCOVID-19ELISASARS-CoV-2

Identifiers

PMID38137955
PMCPMC10745004

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.