Evidence map›Paper›PMID 38137949›Full record

ReviewLife (Basel, Switzerland)2023

The Clinical Application of Platelet-Rich Plasma in the Female Reproductive System: A Narrative Review.

Saaliha Vali, Srdjan Saso, Timothy Bracewell Milnes, James Nicopoullos, Meen-Yau Thum, James Richard Smith, Benjamin P Jones

Abstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Saaliha ValiHammersmith Hospital, Imperial College NHS Trust, London W12 OHS, UK.ORCID 0000-0002-7289-0407
Srdjan SasoHammersmith Hospital, Imperial College NHS Trust, London W12 OHS, UK.
Timothy Bracewell MilnesDepartment of Metabolism, Digestion and Reproduction, Imperial College London, London W12 0NN, UK.
James NicopoullosDepartment of Metabolism, Digestion and Reproduction, Imperial College London, London W12 0NN, UK.
Meen-Yau ThumDepartment of Metabolism, Digestion and Reproduction, Imperial College London, London W12 0NN, UK.
James Richard SmithHammersmith Hospital, Imperial College NHS Trust, London W12 OHS, UK.
Benjamin P JonesHammersmith Hospital, Imperial College NHS Trust, London W12 OHS, UK.ORCID 0000-0002-0391-0443

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Platelet-rich plasma is an autologous plasma containing platelets prepared from fresh whole blood drawn from a peripheral vein. Through processing, it can be prepared to contain supraphysiologic levels of platelets at three to five times greater than the level of normal plasma. PRP has been explored both in vivo and ex vivo in the human endometrium model in its ability to harness the intrinsic regenerative capacity of the endometrium. Intrauterine autologous PRP infusions have been shown to increase endometrial thickness and reduce the rate of intrauterine adhesions. In the setting of recurrent implantation failure, intrauterine infusion of PRP has been shown to increase clinical pregnancy rate. PRP also appears to hold a potential role in select patients with premature ovarian insufficiency, poor ovarian responders and in improving outcomes following frozen-thawed transplantation of autologous ovarian tissue. Further studies are required to explore the potential role of PRP in reproductive medicine further, to help standardise PRP protocols and evaluate which routes of administration are most effective.

Indexed as

endometriumgynaecologyinfertilityplatelet-rich plasmauterus

Identifiers

PMID38137949
PMCPMC10744710

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.