Evidence map›Paper›PMID 38137885›Full record

ReviewLife (Basel, Switzerland)2023

Domestic Animal Models of Central Nervous System Tumors: Focus on Meningiomas.

Michele Tomanelli, Tullio Florio, Gabriela Coronel Vargas, Aldo Pagano, Paola Modesto

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Medroxyprogesterone acetate and meningioma: a global issue.Frontiers in global women's health · 2025
    Article
  3. Article
  4. Ancient Diseases in Vertebrates: Tumours through the Ages.Animals : an open access journal from MDPI · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Michele TomanelliDepartment of Experimental Medicine, University of Genova, 16132 Genova, Italy.ORCID 0000-0002-4010-0677
Tullio FlorioPharmacology Section, Department of Internal Medicine (DIMI), University of Genova, 16126 Genova, Italy.ORCID 0000-0002-2394-996X
Gabriela Coronel VargasDepartment of Experimental Medicine, University of Genova, 16132 Genova, Italy.ORCID 0000-0002-7879-706X
Aldo PaganoDepartment of Experimental Medicine, University of Genova, 16132 Genova, Italy.ORCID 0000-0001-8035-9299
Paola ModestoNational Reference Center for Veterinary and Comparative Oncology, Veterinary Medical Research Institute for Piemonte, Liguria and Valle d'Aosta, 10154 Torino, Italy.ORCID 0000-0002-8865-2366
Ospedale Policlinico San Martino · ITUniversity of Genoa · ITIstituto Zooprofilattico Sperimentale del Piemonte Liguria e Valle d'Aosta · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracranial primary tumors (IPTs) are aggressive forms of malignancies that cause high mortality in both humans and domestic animals. Meningiomas are frequent adult IPTs in humans, dogs, and cats, and both benign and malignant forms cause a decrease in life quality and survival. Surgery is the primary therapeutic approach to treat meningiomas, but, in many cases, it is not resolutive. The chemotherapy and targeted therapy used to treat meningiomas also display low efficacy and many side effects. Therefore, it is essential to find novel pharmacological approaches to increase the spectrum of therapeutic options for meningiomas. This review analyzes the similarities between human and domestic animal (dogs and cats) meningiomas by evaluating the molecular and histological characteristics, diagnosis criteria, and treatment options and highlighting possible research areas to identify novel targets and pharmacological approaches, which are useful for the diagnosis and therapy of this neoplasia to be used in human and veterinary medicine.

Indexed as

cancermeningiomasone healthveterinary medicine

Identifiers

PMID38137885
PMCPMC10744527
OpenAlexW4389191122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.