ArticleLife (Basel, Switzerland)2023
Line-Field Confocal Optical Coherence Tomography (LC-OCT) for Skin Imaging in Dermatology.
Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Noninvasive Multimodal Imaging and Its Role in Diagnosing Skin Lesions in Dermatology: A Systematic Review and Meta-Analysis.American journal of clinical dermatology · 2025Pooled it
- Assessing the Dermal Epidermal Junction of Hyperkeratotic Actinic Keratoses via Line-Field Confocal Optical Coherence Tomography.International journal of dermatology · 2026Trial
- The Effects of an Oral Supplementation of a Natural Keratin Hydrolysate on Skin Aging: A Randomized, Double-Blind, Placebo-Controlled Clinical Study in Healthy Women.Journal of cosmetic dermatology · 2025Trial
- AI-Assisted Basal Cell Carcinoma Analysis in Line-Field Confocal OCT: Exploring Diagnostic Metrics.Journal of biophotonics · 2026Article
- [Line-field confocal optical coherence tomography in the diagnostics and treatment of recurrent Merkel cell carcinoma in the scalp].Dermatologie (Heidelberg, Germany) · 2026Article
- Imaging transcriptomics in basal cell carcinoma: Coupling in vivo tumor morphology with gene expression.JID innovations : skin science from molecules to population health · 2026Article
- Emerging In Vivo and Ex Vivo Optical Imaging Technologies in Dermatology and Dermatopathology.Dermatopathology (Basel, Switzerland) · 2026Review
- Multimodal Non-Invasive Skin Imaging in Dermatology: Current Modalities, Clinical Applications, and Future Integration.Diagnostics (Basel, Switzerland) · 2026Review
- Preclinical Safety and Feasibility Study of Line-Field Confocal Optical Coherence Tomography for Ophthalmology Applications.Translational vision science & technology · 2026Article
- Treatment of keratosis pilaris with laser hair removal as monitored by line-field optical coherence tomography: A proof-of-concept study.JAAD case reports · 2026Article
- Applying RCM-Based Criteria to LC-OCT for Classifying Mucosal Melanoses: A Proof-of-Concept Study.Dermatology practical & conceptual · 2026Article
- Longitudinal Assessment of Vascularity in Actinic Keratosis Using Dynamic Optical Coherence Tomography: Practical Considerations and Theoretical Insights.Journal of biophotonics · 2026Article
- Efficacy of 4% 5-Fluorouracil Cream in the Treatment of Actinic Keratoses: A Single-Center Experience.Journal of clinical medicine · 2026Article
- From skin aging biomarkers to precision esthetic longevity: a translational diagnostic framework.Frontiers in medicine · 2026Article
- A U-Net model for epidermal segmentation in optical coherence tomography images of actinic keratosis.PloS one · 2026Article
- Application of Trichoscopy and Novel Non-Invasive Imaging Techniques in the Diagnosis and Management of Patients with Scalp Psoriasis.Psoriasis (Auckland, N.Z.) · 2026Review
- Label-free human skin imaging with enhanced molecular contrast via time-resolved fluorescence and advanced phasor analysis.Communications biology · 2025Article
- Estimation of Scattering Properties Modifications Caused by In Vivo Human Skin Optical Clearing Using Line-Field Confocal Optical Coherence Tomography.Journal of biophotonics · 2025Article
- Line-Field Confocal Optical Coherence Tomography of Basal Cell Carcinoma: Systematic Correlation with Histopathology.Diagnostics (Basel, Switzerland) · 2025Article
- Line-Field Confocal Optical Coherence Tomography for the Evaluation of Pigmented Skin Lesions of the Genital Area.Diagnostics (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Line-field confocal optical coherence tomography (LC-OCT) is a non-invasive optical imaging technique based on a combination of the principles of optical coherence tomography and reflectance confocal microscopy with line-field illumination, which can generate cell-resolved images of the skin in vivo. This article reports on the LC-OCT technique and its application in dermatology. The principle of the technique is described, and the latest technological innovations are presented. The technology has been miniaturized to fit within an ergonomic handheld probe, allowing for the easy access of any skin area on the body. The performance of the LC-OCT device in terms of resolution, field of view, and acquisition speed is reported. The use of LC-OCT in dermatology for the non-invasive detection, characterization, and therapeutic follow-up of various skin pathologies is discussed. Benign and malignant melanocytic lesions, non-melanocytic skin tumors, such as basal cell carcinoma, squamous cell carcinoma and actinic keratosis, and inflammatory and infectious skin conditions are considered. Dedicated deep learning algorithms have been developed for assisting in the analysis of LC-OCT images of skin lesions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.