Evidence map›Paper›PMID 38137611›Full record

ArticleJournal of clinical medicine2023

COVID-19 Vaccination-Related Delayed Adverse Events among Patients with Systemic Lupus Erythematosus.

Mrinalini Dey, Bohdana Doskaliuk, Julius Lindblom, Elena Nikiphorou, Chris Wincup, Madiha Fathima, Sreoshy Saha, Syahrul Sazliyana Shaharir, Wanruchada Katchamart, Phonpen Akarawatcharangura Goo and 16 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 16 institutions in 12 countries.

Mrinalini DeyCentre for Rheumatic Diseases, King's College London, Weston Education Centre, Cutcombe Road, London SE5 9RJ, UK.ORCID 0000-0001-6858-4338
Bohdana DoskaliukDepartment of Pathophysiology, Ivano-Frankivsk National Medical University, 76018 Ivano-Frankivsk, Ukraine.
Julius LindblomDivision of Rheumatology, Department of Medicine Solna, Karolinska Institutet and Karolinska University Hospital, 17176 Stockholm, Sweden.ORCID 0000-0003-1582-9471
Elena NikiphorouCentre for Rheumatic Diseases, King's College London, Weston Education Centre, Cutcombe Road, London SE5 9RJ, UK.
Chris WincupRheumatology Department, King's College Hospital, London SE5 9RS, UK.
Madiha FathimaDivision of Rheumatology, Department of Medicine Solna, Karolinska Institutet and Karolinska University Hospital, 17176 Stockholm, Sweden.
Sreoshy SahaMymensingh Medical College, Mymensingh 2200, Bangladesh.
Syahrul Sazliyana ShaharirFaculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur 56000, Malaysia.
Wanruchada KatchamartDivision of Rheumatology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10100, Thailand.
Phonpen Akarawatcharangura GooDepartment of Medicine, Queen Savang Vadhana Memorial Hospital, Chonburi 20000, Thailand.
Lisa TrabocoDepartment of Medicine, Section of Rheumatology, St. Luke's Medical Center-Global City, Taguig 1630, Philippines.
Yi-Ming ChenDivision of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung 402, Taiwan.ORCID 0000-0001-7593-3065
Esha KadamSeth Gordhandhas Sunderdas Medical College and King Edwards Memorial Hospital, Mumbai 400001, Maharashtra, India.
James B LillekerDivision of Musculoskeletal and Dermatological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester M13 9PL, UK.
Arvind NuneSouthport and Ormskirk Hospital NHS Trust, Southport PR8 6PN, UK.ORCID 0000-0002-3849-614X
John D PaulingBristol Medical School Translational Health Sciences, University of Bristol, Bristol BS8 1QU, UK.
Vishwesh AgarwalMahatma Gandhi Mission Medical College, Navi Mumbai 401208, Maharashtra, India.ORCID 0000-0002-0986-8354
Dzifa DeyRheumatology Unit, Department of Medicine and Therapeutics, University of Ghana Medical School, College of Health Sciences, Korle-Bu, Accra KB 460, Ghana.
Carlos Enrique Toro GutierrezReference Center for Osteoporosis, Rheumatology and Dermatology, Pontifica Universidad Javeriana Cali, Cali 760046, Colombia.
Carlo Vinicio CaballeroDepartment of Medicine, Hospital Universidad del Norte, Barranquilla 081001, Colombia.
Hector ChinoyDivision of Musculoskeletal and Dermatological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester M13 9PL, UK.
Covad Study GroupDivision of Rheumatology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10100, Thailand.
Rohit AggarwalDivision of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.ORCID 0000-0001-7531-8038
Vikas AgarwalDepartment of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, Uttar Pradesh, India.ORCID 0000-0002-4508-1233
Latika GuptaDivision of Musculoskeletal and Dermatological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester M13 9PL, UK.
Ioannis ParodisDivision of Rheumatology, Department of Medicine Solna, Karolinska Institutet and Karolinska University Hospital, 17176 Stockholm, Sweden.ORCID 0000-0002-4875-5395
Karolinska University Hospital · SESanjay Gandhi Post Graduate Institute of Medical Sciences · INSiriraj Hospital · THKing's College London · GBManchester Academic Health Science Centre · GBIvano-Frankivsk National Medical University · UAKing Edward Memorial Hospital and Seth G.S. Medical College · INKing's College Hospital · GBMymensingh Medical College Hospital · BDNorth Bristol NHS Trust · GBPontificia Universidad Javeriana · COSouthport and Ormskirk Hospital NHS Trust · GBSt. Luke's Medical Center · PHTaichung Veterans General Hospital · TWUniversidad del Norte · COUniversity of Ghana · GH

Funding

Versus Arthritis 21992
6 · The paper itself

Abstract

backgroundThe safety profile of COVID-19 vaccination is well documented, but hesitancy among people with immune-mediated inflammatory diseases, often immunocompromised, remains high, partially due to a scarcity of data on safety over a longer term. We herein aimed to assess delayed adverse events (DAEs) occurring >7 days after COVID-19 vaccination in systemic lupus erythematosus (SLE) versus other rheumatic autoimmune diseases (rAIDs), non-rheumatic AIDs (nrAIDs), and healthy controls (HCs).

methodsSelf-reported data were captured within the COVID-19 Vaccination in Autoimmune Diseases (COVAD)-2 online survey, which comprised >150 centres and responses from 106 countries, between February and June 2022. Logistic regression analysis adjusting for important confounders (age, sex, ethnicity) was used to compare groups.

resultsOf 7203 eligible individuals, 882 (12.2%) patients had SLE, 3161 (43.9%) patients had rAIDs, 426 (5.9%) patients had nrAIDs, and 2734 (38.0%) were HCs. SLE patients had a median age of 39 years (IQR: 31-50); 93.7% were women. SLE patients reported, more frequently, major DAEs (OR: 1.6; 95% CI: 1.2-2.0;

conclusionHospitalisations post-vaccination were more frequent in SLE patients than in HCs. Monitoring of SLE patients following COVID-19 vaccination can help in identifying DAEs early, informing patients about expected DAEs, and supporting patients, especially those with autoimmune multimorbidity.

Indexed as

COVID-19delayed adverse eventssystemic lupus erythematosusvaccines

Identifiers

PMID38137611
PMCPMC10743599
OpenAlexW4389441192

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.