Evidence map›Paper›PMID 38137568›Full record

ReviewBiomedicines2023

Recent Therapeutic Progress and Future Perspectives for the Treatment of Hearing Loss.

Joey Lye, Derek S Delaney, Fiona K Leith, Varda S Sardesai, Samuel McLenachan, Fred K Chen, Marcus D Atlas, Elaine Y M Wong

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Joey LyeHearing Therapeutics, Ear Science Institute Australia, Nedlands, WA 6009, Australia.ORCID 0009-0002-3906-9948
Derek S DelaneyHearing Therapeutics, Ear Science Institute Australia, Nedlands, WA 6009, Australia.ORCID 0000-0002-1185-121X
Fiona K LeithHearing Therapeutics, Ear Science Institute Australia, Nedlands, WA 6009, Australia.
Varda S SardesaiHearing Therapeutics, Ear Science Institute Australia, Nedlands, WA 6009, Australia.
Samuel McLenachanOcular Tissue Engineering Laboratory, Lions Eye Institute, Nedlands, WA 6009, Australia.
Fred K ChenOcular Tissue Engineering Laboratory, Lions Eye Institute, Nedlands, WA 6009, Australia.
Marcus D AtlasHearing Therapeutics, Ear Science Institute Australia, Nedlands, WA 6009, Australia.
Elaine Y M WongHearing Therapeutics, Ear Science Institute Australia, Nedlands, WA 6009, Australia.
The University of Western Australia · AULions Eye Institute · AUCurtin University · AUEar Science Institute Australia · AU

Funding

Australian government National Health and Medical Research Council (NHMRC) Medical Research Future Fund (MRFF) Stem Cell Therapies Mission Grant APP2017281Commonwealth Scientific and Industrial Research Organisation P12-1426Future Health Research and Innovation Fund (FHRIF) Near-miss Awards: Ideas Grants (WANMA) WANMA/IG2021/6
6 · The paper itself

Abstract

Up to 1.5 billion people worldwide suffer from various forms of hearing loss, with an additional 1.1 billion people at risk from various insults such as increased consumption of recreational noise-emitting devices and ageing. The most common type of hearing impairment is sensorineural hearing loss caused by the degeneration or malfunction of cochlear hair cells or spiral ganglion nerves in the inner ear. There is currently no cure for hearing loss. However, emerging frontier technologies such as gene, drug or cell-based therapies offer hope for an effective cure. In this review, we discuss the current therapeutic progress for the treatment of hearing loss. We describe and evaluate the major therapeutic approaches being applied to hearing loss and summarize the key trials and studies.

Indexed as

cell therapygene therapyhair cellhearing lossinner eartherapeutics

Identifiers

PMID38137568
PMCPMC10741758
OpenAlexW4389882381

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.