Evidence map›Paper›PMID 38137511›Full record

ArticleBiomedicines2023

Genomic Landscape Comparison of Cardiac versus Extra-Cardiac Angiosarcomas.

Livia Gozzellino, Margherita Nannini, Milena Urbini, Carmine Pizzi, Ornella Leone, Barbara Corti, Chiara Baldovini, Francesco Angeli, Alberto Foà, Davide Pacini and 7 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Livia GozzellinoDepartment of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum-University of Bologna, 40138 Bologna, Italy.
Margherita NanniniDepartment of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum-University of Bologna, 40138 Bologna, Italy.ORCID 0000-0002-2103-1960
Milena UrbiniBiosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.ORCID 0000-0002-3364-9098
Carmine PizziUnit of Cardiology, Department of Medical and Surgical Sciences, University of Bologna, 40138 Bologna, Italy.ORCID 0000-0002-4048-675X
Ornella LeoneDivision of Pathology, Cardiovascular and Cardiac Transplant Pathology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Barbara CortiDivision of Pathology, Cardiovascular and Cardiac Transplant Pathology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Chiara BaldoviniDivision of Pathology, Cardiovascular and Cardiac Transplant Pathology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.ORCID 0000-0002-1499-4654
Francesco AngeliDepartment of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum-University of Bologna, 40138 Bologna, Italy.
Alberto FoàUnit of Cardiology, Department of Medical and Surgical Sciences, University of Bologna, 40138 Bologna, Italy.
Davide PaciniCardiac Surgery Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Gianluca FolesaniCardiac Surgery Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Alice CostaIRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.ORCID 0000-0003-0809-2512
Teresa PalumboInterdepartmental Center Alma Mater Institute on Healthy Planet, Alma Mater Studiorum-University of Bologna, 40138 Bologna, Italy.
Maria Concetta NigroDepartment of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum-University of Bologna, 40138 Bologna, Italy.ORCID 0000-0003-3834-6122
Gianandrea PasquinelliDivision of Pathology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.ORCID 0000-0003-1506-1829
Annalisa AstolfiDepartment of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum-University of Bologna, 40138 Bologna, Italy.ORCID 0000-0002-2732-0747
Maria Abbondanza PantaleoDepartment of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum-University of Bologna, 40138 Bologna, Italy.
Azienda USL di Bologna · ITUniversity of Bologna · ITIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori · IT

Funding

Italian Ministry of Health RC-2022-2773439
6 · The paper itself

Abstract

Angiosarcomas (ASs) are rare malignant vascular entities that can affect several regions in our body, including the heart. Cardiac ASs comprise 25-40% of cardiac sarcomas and can cause death within months of diagnosis. Thus, our aim was to identify potential differences and/or similarities between cardiac and extra-cardiac ASs to enhance targeted therapies and, consequently, patients' prognosis. Whole-transcriptome analysis of three cardiac and eleven extra-cardiac non-cutaneous samples was performed to investigate differential gene expression and mutational events between the two groups. The gene signature of cardiac and extra-cardiac non-cutaneous ASs was also compared to that of cutaneous angiosarcomas (n = 9).

Indexed as

bioinformaticscardiac angiosarcomasextra-cardiac angiosarcomaswhole-transcriptome sequencing

Identifiers

PMID38137511
PMCPMC10741871
OpenAlexW4389627072

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.