Evidence map›Paper›PMID 38137502›Full record

ArticleBiomedicines2023

Erucin Exerts Cardioprotective Effects on Ischemia/Reperfusion Injury through the Modulation of mitoKATP Channels.

Lorenzo Flori, Rosangela Montanaro, Eleonora Pagnotta, Luisa Ugolini, Laura Righetti, Alma Martelli, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Vincenzo Brancaleone, Lara Testai and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Evolution of Secondary Metabolites inFoods (Basel, Switzerland) · 2025
    Article
  2. The potential role of hydrogen sulfide-autophagy axis in diseases.Journal of physiology and biochemistry · 2025
    Review
  3. Review
  4. Article
  5. Review
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Lorenzo FloriDepartment of Pharmacy, University of Pisa, 56120 Pisa, Italy.ORCID 0000-0001-7899-0954
Rosangela MontanaroDepartment of Science, University of Basilicata, 85100 Potenza, Italy.ORCID 0009-0007-0678-6066
Eleonora PagnottaResearch Centre for Cereal and Industrial Crops, CREA-Council for Agricultural Research and Economics, Via di Corticella 133, 40128 Bologna, Italy.ORCID 0000-0002-9477-1724
Luisa UgoliniResearch Centre for Cereal and Industrial Crops, CREA-Council for Agricultural Research and Economics, Via di Corticella 133, 40128 Bologna, Italy.ORCID 0000-0001-7954-6257
Laura RighettiResearch Centre for Cereal and Industrial Crops, CREA-Council for Agricultural Research and Economics, Via di Corticella 133, 40128 Bologna, Italy.ORCID 0000-0002-5421-7630
Alma MartelliDepartment of Pharmacy, University of Pisa, 56120 Pisa, Italy.ORCID 0000-0002-2090-7107
Lorenzo Di Cesare MannelliPharmacology and Toxicology Section, Department of Neuroscience, Psychology, Drug Research and Child Health (NEUROFARBA), University of Florence, 50139 Florence, Italy.ORCID 0000-0001-8374-4432
Carla GhelardiniPharmacology and Toxicology Section, Department of Neuroscience, Psychology, Drug Research and Child Health (NEUROFARBA), University of Florence, 50139 Florence, Italy.
Vincenzo BrancaleoneDepartment of Science, University of Basilicata, 85100 Potenza, Italy.ORCID 0000-0002-0063-659X
Lara TestaiDepartment of Pharmacy, University of Pisa, 56120 Pisa, Italy.ORCID 0000-0003-2431-6248
Vincenzo CalderoneDepartment of Pharmacy, University of Pisa, 56120 Pisa, Italy.
University of Pisa · ITResearch Centre for Cereal and Industrial Crops · ITUniversity of Basilicata · ITUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modulation of mitochondrial K channels represents a pharmacological strategy to promote cardioprotective effects. Isothiocyanates emerge as molecules capable of releasing hydrogen sulfide (H

Indexed as

5-HDerucinH2SH2S donorsischemia/reperfusionisothiocyanatesmitochondrial channelsmitoKATP channels

Identifiers

PMID38137502
PMCPMC10740937
OpenAlexW4389624608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.