Evidence map›Paper›PMID 38137368›Full record

ArticleBiomedicines2023

Understanding the Episodic Memory and Executive Functioning Axis Impairment in MCI Patients: A Multicenter Study in Comparison with CSF Biomarkers.

Brenda Chino, Lucía Torres-Simón, Agnieszka Żelwetro, Inmaculada Concepción Rodríguez-Rojo, Anna Carnes-Vendrell, Gerard Piñol-Ripoll, Raquel Yubero, Nuria Paúl, Fernando Maestú

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Brenda ChinoInstitute of Neuroscience, Autonomous University of Barcelona (UAB), 08193 Barcelona, Spain.ORCID 0000-0002-8169-263X
Lucía Torres-SimónCenter for Cognitive and Computational Neuroscience, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Agnieszka ŻelwetroInterdisciplinary Doctoral School, SWPS University of Social Sciences and Humanities, 53-238 Wrocław, Poland.
Inmaculada Concepción Rodríguez-RojoCenter for Cognitive and Computational Neuroscience, Universidad Complutense de Madrid, 28040 Madrid, Spain.ORCID 0000-0003-2781-3004
Anna Carnes-VendrellUnitat de Trastorns Cognitius, Cognition and Behavior Study Group, Universitat de Lleida, IRBLleida, 25198 Lleida, Spain.ORCID 0000-0003-2211-380X
Gerard Piñol-RipollUnitat de Trastorns Cognitius, Cognition and Behavior Study Group, Universitat de Lleida, IRBLleida, 25198 Lleida, Spain.
Raquel YuberoNeurology Department, Hospital Quirónsalud Madrid, 28223 Madrid, Spain.
Nuria PaúlDepartment of Experimental Psychology, Cognitive Processes and Speech Therapy, Universidad Complutense de Madrid, 28040 Madrid, Spain.ORCID 0000-0001-5462-6138
Fernando MaestúCenter for Cognitive and Computational Neuroscience, Universidad Complutense de Madrid, 28040 Madrid, Spain.ORCID 0000-0002-3195-0071
Universidad Complutense de Madrid · ESUniversitat de Lleida · ESHospital Universitario Quirónsalud Madrid · ESUniwersytet SWPS · PL

Funding

Biomedical Research Institute of Lleida B.0000682Consejo Nacional de Ciencia, Tecnología e Innovación TecnológicaUniversidad Complutense de Madrid CT42/18-CT43/18
6 · The paper itself

Abstract

backgroundThis study aimed to explore the association between a verbal learning task that evaluates the potential mutual dependency between memory and executive functions (i.e., the Test of Memory Strategies, TMS) and cerebrospinal fluid (CSF) Alzheimer's Disease (AD) biomarkers.

methodsA sample of 47 mild cognitive impairment (MCI) participants from Poland and Spain were classified according to the Erlangen Score Diagnostic Algorithm (ESA) into CSF- (

resultsSignificant associations between the TMS-3 condition and Aβ42, t-tau, and p-tau were observed for the whole sample. In addition, the CSF- participants obtained higher cognitive performance in TMS-3 compared to the CSF+ group. This outcome persisted if the groups were based on Aβ42 scores, but not t-tau or p-tau values.

conclusionsThese findings could indicate that poor performance on verbal learning tests may be affected by executive dysfunctions. Therefore, future intervention plans focused on training executive functions would be of interest to improve the ability of MCI patients to encode and organize information.

Indexed as

CSF biomarkersepisodic memoryexecutive functionsmild cognitive impairmentneuropsychologytest of memory strategies

Identifiers

PMID38137368
PMCPMC10741228
OpenAlexW4389049720

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.