Evidence map›Paper›PMID 38137171›Full record

ReviewBrain sciences2023

Limitations in Evaluating Machine Learning Models for Imbalanced Binary Outcome Classification in Spine Surgery: A Systematic Review.

Marc Ghanem, Abdul Karim Ghaith, Victor Gabriel El-Hajj, Archis Bhandarkar, Andrea de Giorgio, Adrian Elmi-Terander, Mohamad Bydon

Abstract readReview
In one paragraph

Review in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marc GhanemMayo Clinic Neuro-Informatics Laboratory, Mayo Clinic, Rochester, MN 55902, USA.ORCID 0000-0002-7479-7994
Abdul Karim GhaithMayo Clinic Neuro-Informatics Laboratory, Mayo Clinic, Rochester, MN 55902, USA.ORCID 0000-0002-9600-609X
Victor Gabriel El-HajjMayo Clinic Neuro-Informatics Laboratory, Mayo Clinic, Rochester, MN 55902, USA.ORCID 0000-0001-9479-761X
Archis BhandarkarMayo Clinic Neuro-Informatics Laboratory, Mayo Clinic, Rochester, MN 55902, USA.
Andrea de GiorgioArtificial Engineering, Via del Rione Sirignano, 80121 Naples, Italy.ORCID 0000-0001-6064-5634
Adrian Elmi-TeranderDepartment of Clinical Neuroscience, Karolinska Institutet, 17177 Stockholm, Sweden.ORCID 0000-0002-3776-6136
Mohamad BydonMayo Clinic Neuro-Informatics Laboratory, Mayo Clinic, Rochester, MN 55902, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical prediction models for spine surgery applications are on the rise, with an increasing reliance on machine learning (ML) and deep learning (DL). Many of the predicted outcomes are uncommon; therefore, to ensure the models' effectiveness in clinical practice it is crucial to properly evaluate them. This systematic review aims to identify and evaluate current research-based ML and DL models applied for spine surgery, specifically those predicting binary outcomes with a focus on their evaluation metrics. Overall, 60 papers were included, and the findings were reported according to the PRISMA guidelines. A total of 13 papers focused on lengths of stay (LOS), 12 on readmissions, 12 on non-home discharge, 6 on mortality, and 5 on reoperations. The target outcomes exhibited data imbalances ranging from 0.44% to 42.4%. A total of 59 papers reported the model's area under the receiver operating characteristic (AUROC), 28 mentioned accuracies, 33 provided sensitivity, 29 discussed specificity, 28 addressed positive predictive value (PPV), 24 included the negative predictive value (NPV), 25 indicated the Brier score with 10 providing a null model Brier, and 8 detailed the F1 score. Additionally, data visualization varied among the included papers. This review discusses the use of appropriate evaluation schemes in ML and identifies several common errors and potential bias sources in the literature. Embracing these recommendations as the field advances may facilitate the integration of reliable and effective ML models in clinical settings.

Indexed as

artificial intelligencedeep learningmachine learningpredictive modelingspine surgery

Identifiers

PMID38137171
PMCPMC10741524

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.