Evidence map›Paper›PMID 38137130›Full record

ReviewBrain sciences2023

Delirium after Cardiac Surgery-A Narrative Review.

Daniel Mattimore, Adrian Fischl, Alexa Christophides, Jerry Cuenca, Steven Davidson, Zhaosheng Jin, Sergio Bergese

2 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07151716 phase4completednot on this mapstarted 2025, after this paper: background citation

Effect of Sedation With Dexmedetomidine-esketamine Combination on Delirium in Postoperative ICU Patients: a Randomized Controlled Pilot Trial

TypeinterventionalSponsorPeking University First HospitalRan2025 to 2026Enrolled100ConditionsOlder Patients, Postoperative Care, Intensive Care Unit, DexmedetomidineArmsDexmedetomidine, Dexmedetomidine-esketamine combination
NCT07249047 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Correlation Between Optic Nerve Sheath Diameter Measured by Ultrasound and Delirium in Cardiac Surgery

TypeinterventionalSponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sRan2026 to 2027Enrolled300ConditionsPostoperative DeliriumArmsOptic nerve sheath diameter (ONSD) ultrasound
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Article
  13. Thiamine Use in Hospitalized Patients: A Clinical Review.Journal of nutrition and metabolism · 2026
    Review
  14. Article
  15. Review
  16. Article
  17. Observational
  18. Article
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Daniel MattimoreDepartment of Anesthesiology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Adrian FischlDepartment of Anesthesiology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Alexa ChristophidesDepartment of Anesthesiology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Jerry CuencaDepartment of Anesthesiology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Steven DavidsonDepartment of Anesthesiology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Zhaosheng JinDepartment of Anesthesiology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Sergio BergeseDepartment of Anesthesiology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Stony Brook University Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postoperative delirium (POD) after cardiac surgery is a well-known phenomenon which carries a higher risk of morbidity and mortality. Multiple patient-specific risk factors and pathophysiologic mechanisms have been identified and therapies have been proposed to mitigate risk of delirium development postoperatively. Notably, cardiac surgery frequently involves the use of an intraoperative cardiopulmonary bypass (CPB), which may contribute to the mechanisms responsible for POD. Despite our greater understanding of these causative factors, a substantial reduction in the incidence of POD remains high among cardiac surgical patients. Multiple therapeutic interventions have been implemented intraoperatively and postoperatively, many with conflicting results. This review article will highlight the incidence and impact of POD in cardiac surgical patients. It will describe some of the primary risk factors associated with POD, as well as anesthetic management and therapies postoperatively that may help to reduce delirium.

Indexed as

cardiac surgerycardiopulmonary bypasspostoperative delirium

Identifiers

PMID38137130
PMCPMC10741583
OpenAlexW4389441322

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.