Evidence map›Paper›PMID 38137098›Full record

ArticleBrain sciences2023

Rescuing Infected Deep Brain Stimulation Therapies in Severely Affected Patients.

Thomas Fortmann, Samer Zawy Alsofy, Marc Lewitz, Antonio Santacroce, Heinz Welzel Saravia, Ioanna Sakellaropoulou, Eike Wilbers, Steffen Grabowski, Ralf Stroop, Zafer Cinibulak and 2 more

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Thomas FortmannDepartment of Medicine, Faculty of Health, Witten/Herdecke University, 58448 Witten, Germany.
Samer Zawy AlsofyDepartment of Medicine, Faculty of Health, Witten/Herdecke University, 58448 Witten, Germany.ORCID 0000-0002-9592-3881
Marc LewitzDepartment of Medicine, Faculty of Health, Witten/Herdecke University, 58448 Witten, Germany.
Antonio SantacroceDepartment of Medicine, Faculty of Health, Witten/Herdecke University, 58448 Witten, Germany.
Heinz Welzel SaraviaDepartment of Neurosurgery, St. Barbara-Hospital, Academic Hospital of Westfaelische Wilhelms-University Muenster, 59073 Hamm, Germany.
Ioanna SakellaropoulouDepartment of Neurosurgery, St. Barbara-Hospital, Academic Hospital of Westfaelische Wilhelms-University Muenster, 59073 Hamm, Germany.
Eike WilbersDepartment of Medicine, Faculty of Health, Witten/Herdecke University, 58448 Witten, Germany.
Steffen GrabowskiDepartment of Neurosurgery, St. Barbara-Hospital, Academic Hospital of Westfaelische Wilhelms-University Muenster, 59073 Hamm, Germany.
Ralf StroopDepartment of Medicine, Faculty of Health, Witten/Herdecke University, 58448 Witten, Germany.
Zafer CinibulakDepartment of Medicine, Faculty of Health, Witten/Herdecke University, 58448 Witten, Germany.
Makoto NakamuraDepartment of Medicine, Faculty of Health, Witten/Herdecke University, 58448 Witten, Germany.
Ralph LehrkeDepartment of Stereotactic Neurosurgery, St. Barbara-Hospital, Academic Hospital of Westfaelische Wilhelms-University Muenster, 59073 Hamm, Germany.
Witten/Herdecke University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Infections in deep brain stimulation (DBS) hardware, while an undesired complication of DBS surgeries, can be effectively addressed. Minor infections are typically treated with wound revision and IV antibiotics. However, when visible hardware infection occurs, most centers opt for complete removal, leaving the patient in a preoperative state and necessitating post-removal care. To avoid the need for such care, a novel technique was developed. (2) Methods: The electrodes are placed at the exact same spot and then led to the contralateral side. new extensions and a new generator contralateral to the infection as well. Subsequently, the infected system is removed. This case series includes six patients. (3) Results: The average duration of DBS system implantation before the second surgery was 272 days. Only one system had to be removed after 18 months due to reoccurring infection; the others remained unaffected. Laboratory alterations and pathogens were identified in only half of the patients. (4) Conclusions: The described surgical technique proves to be safe, well tolerated, and serves as a viable alternative to complete system removal. Importantly, it effectively prevents the need of post-removal care for patients.

Indexed as

deep brain stimulationinfectionsalvage surgery

Identifiers

PMID38137098
PMCPMC10742038
OpenAlexW4389085154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.