Evidence map›Paper›PMID 38137051›Full record

ReviewGenes2023

Soft Tissue and Bone Tumor Diagnostics: Harnessing the Power of Molecular Techniques.

Fleur Cordier, Liesbeth Ferdinande, Anne Hoorens, Koen Van de Vijver, Jo Van Dorpe, David Creytens

Abstract readReview
In one paragraph

Review in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fleur CordierDepartment of Pathology, Ghent University Hospital, Ghent University, 9000 Ghent, Belgium.
Liesbeth FerdinandeDepartment of Pathology, Ghent University Hospital, Ghent University, 9000 Ghent, Belgium.
Anne HoorensDepartment of Pathology, Ghent University Hospital, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0002-0736-2034
Koen Van de VijverDepartment of Pathology, Ghent University Hospital, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0002-2026-9790
Jo Van DorpeDepartment of Pathology, Ghent University Hospital, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0001-8175-2930
David CreytensDepartment of Pathology, Ghent University Hospital, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0002-6064-1673

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the introduction of new molecular techniques, the diagnostic landscape of soft tissue and bone tumors has expanded greatly over the past few years. The use of new molecular techniques has led to the identification of new genetic alterations and, therefore, to a better understanding of tumorigenesis, tumor detection and classification. Furthermore, methylation profiling has emerged as a classification tool for soft tissue and bone tumors. Molecular pathology also plays an important role in the determination of patient prognosis and in the identification of targets that can be used for targeted therapy. As a result, molecular pathology has gained a more prominent role in the daily practice of the surgical pathologist. This review delves into various molecular techniques applied in the surgical pathology of soft tissue and bone tumors. It highlights their applications through the analysis of five specific cases.

Indexed as

Bone NeoplasmsSoft Tissue NeoplasmsHumansMutationPathology, MolecularPrognosiscopy number variation sequencingDNA/RNA-based next-generation sequencingfluorescence in situ hybridizationimmunohistochemistrymethylation profilingmolecular pathologysoft tissue tumors

Identifiers

PMID38137051
PMCPMC10742688

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.