Evidence map›Paper›PMID 38136953›Full record

ReviewGenes2023

Oligo-Metastatic Disease in Oncology: Exploring the Limits and the Potential of Genetic Assessment.

Mariachiara Santorsola, Maurizio Capuozzo, Giovanni Savarese, Monica Ianniello, Nadia Petrillo, Marika Casillo, Francesco Sabbatino, Francesco Perri, Francesco Ferrara, Andrea Zovi and 4 more

Abstract readReview
In one paragraph

Review in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mariachiara SantorsolaIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale", Via Mariano Semmola, 80131 Napoli, Italy.
Maurizio CapuozzoCoordinamento Farmaceutico, ASL-Naples-3, 80056 Ercolano, Italy.ORCID 0000-0001-9488-6057
Giovanni SavareseAMES, Centro Polidiagnostico Strumentale srl, Via Padre Carmine Fico 24, 80013 Casalnuovo Di Napoli, Italy.
Monica IannielloAMES, Centro Polidiagnostico Strumentale srl, Via Padre Carmine Fico 24, 80013 Casalnuovo Di Napoli, Italy.
Nadia PetrilloAMES, Centro Polidiagnostico Strumentale srl, Via Padre Carmine Fico 24, 80013 Casalnuovo Di Napoli, Italy.
Marika CasilloAMES, Centro Polidiagnostico Strumentale srl, Via Padre Carmine Fico 24, 80013 Casalnuovo Di Napoli, Italy.ORCID 0000-0001-7736-8194
Francesco SabbatinoDepartment of Medicine, Surgery and Dentistry, University of Salerno, 84081 Baronissi, Italy.ORCID 0000-0001-6431-8278
Francesco PerriIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale", Via Mariano Semmola, 80131 Napoli, Italy.ORCID 0000-0001-8158-7509
Francesco FerraraHospital Pharmacist Manager, Pharmaceutical Department, Asl Napoli 3 Sud, Via Dell'amicizia 22, 80035 Nola, Italy.
Andrea ZoviHospital Pharmacist, Ministry of Health, Viale Giorgio Ribotta 5, 00144 Rome, Italy.ORCID 0000-0002-6528-2171
Massimiliano BerrettaDepartment of Clinical and Experimental Medicine, University of Messina, 98122 Messina, Italy.
Vincenza GranataIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale", Via Mariano Semmola, 80131 Napoli, Italy.ORCID 0000-0002-6601-3221
Guglielmo NastiIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale", Via Mariano Semmola, 80131 Napoli, Italy.
Alessandro OttaianoIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale", Via Mariano Semmola, 80131 Napoli, Italy.ORCID 0000-0002-2901-3855

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oligo-metastatic disease (OMD) in the field of oncology denotes a distinct subset of metastatic tumors characterized by less aggressive biological behavior and extended survival times in comparison to their widely metastatic counterparts. While there is a general consensus regarding the existence of OMD, there remains a lack of widely accepted criteria for its a priori identification at the time of presentation. This review delves into the concept of OMD, placing a particular emphasis on the significance of understanding the limitations and potential of genetic assessments. It explores how these aspects are crucial in advancing our comprehension of this phenomenon. In a rapidly advancing era of precision medicine, understanding the intricacies of OMD opens up exciting possibilities for tailored treatment approaches. By elucidating the genetic underpinnings and dynamic nature of this condition, we stand to improve patient outcomes and potentially shift the paradigm of metastatic cancer management.

Indexed as

NeoplasmsNeoplasms, Second PrimaryHumansgeneticsliquid biopsyNGSoligo-metastatic disease

Identifiers

PMID38136953
PMCPMC10742616

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.