Evidence map›Paper›PMID 38136945›Full record

ArticleGenes2023

Genome-Wide Association Study of Blood Mercury in European Pregnant Women and Children.

Kyle Dack, Mariona Bustamante, Caroline M Taylor, Sabrina Llop, Manuel Lozano, Paul Yousefi, Regina Gražulevičienė, Kristine Bjerve Gutzkow, Anne Lise Brantsæter, Dan Mason and 2 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 4 countries.

Kyle DackMedical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol BS8 1TH, UK.ORCID 0000-0003-0319-590X
Mariona BustamanteISGlobal, Institute for Global Health, 08036 Barcelona, Spain.ORCID 0000-0003-0127-2860
Caroline M TaylorCentre for Academic Child Health, Bristol Medical School, University of Bristol, Bristol BS8 2PS, UK.ORCID 0000-0001-8347-5092
Sabrina LlopSpanish Consortium for Research on Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain.
Manuel LozanoEpidemiology and Environmental Health Joint Research Unit, FISABIO- Universitat Jaume I - Universitat de València, 46020 Valencia, Spain.ORCID 0000-0003-2046-5959
Paul YousefiMedical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol BS8 1TH, UK.ORCID 0000-0003-3284-3240
Regina GražulevičienėDepartment of Environmental Sciences, Faculty of Natural Sciences, Vytautas Magnus University, 53361 Kaunas, Lithuania.
Kristine Bjerve GutzkowDepartment of Air Quality and Noise, Division of Climate and Environmental Health, Norwegian Institute of Public Health, P.O. Box 222 Skoyen, NO-0213 Oslo, Norway.
Anne Lise BrantsæterDepartment of Food Safety, Division of Climate and Environmental Health, Norwegian Institute of Public Health, P.O. Box 222 Skoyen, NO-0213 Oslo, Norway.ORCID 0000-0001-6315-7134
Dan MasonBradford Teaching Hospitals NHS Foundation Trust, Duckworth Lane, Bradford BD9 6RJ, UK.ORCID 0000-0002-0026-9216
Georgia EscaramísSpanish Consortium for Research on Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain.
Sarah J LewisMedical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol BS8 1TH, UK.ORCID 0000-0003-4311-6890
University of Bristol · GBNorwegian Institute of Public Health · NOUniversitat Jaume I · ESBradford Teaching Hospitals NHS Foundation Trust · GBCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública · ESUniversitat Pompeu Fabra · ESVytautas Magnus University · LT

Funding

Intramural NIH HHSMedical Research Council G9815508Medical Research Council MC_PC_15018Medical Research Council MC_PC_19009Medical Research Council MC_UU_00011/1Medical Research Council MC_UU_00011/5Medical Research Council MR/N024397/1Medical Research Council MR/T010010/1Medical Research Council UK 217065/Z/19/ZWellcome TrustWellcome Trust WT088806Wellcome Trust WT101597MA
6 · The paper itself

Abstract

Mercury has high industrial utility and is present in many products, and environmental contamination and occupational exposure are widespread. There are numerous biological systems involved in the absorption, metabolism, and excretion of Hg, and it is possible that some systems may be impacted by genetic variation. If so, genotype may affect tissue concentrations of Hg and subsequent toxic effects. Genome-wide association testing was performed on blood Hg samples from pregnant women of the Avon Longitudinal Study of Parents and Children (

Indexed as

Genome-Wide Association StudyMercuryChildFemaleGenotypeHumansLongitudinal StudiesPregnancyPregnant PeopleMercuryALSPACblood mercurychildrenGWASHELIXpregnancy

Identifiers

PMID38136945
PMCPMC10742428
OpenAlexW4388969308

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.