Evidence map›Paper›PMID 38136755›Full record

ArticleAntibiotics (Basel, Switzerland)2023

The Etiology, Antibiotic Therapy and Outcomes of Bacteremic Skin and Soft-Tissue Infections in Onco-Hematological Patients.

Valeria Castelli, Enric Sastre-Escolà, Pedro Puerta-Alcalde, Leyre Huete-Álava, Júlia Laporte-Amargós, Alba Bergas, Mariana Chumbita, Mar Marín, Eva Domingo-Domenech, Ana María Badia-Tejero and 4 more

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 2 countries.

Valeria CastelliInfectious Diseases Department, Bellvitge University Hospital, Bellvitge Biomedical Research Institute (IDIBELL), University of Barcelona, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Enric Sastre-EscolàInfectious Diseases Department, Bellvitge University Hospital, Bellvitge Biomedical Research Institute (IDIBELL), University of Barcelona, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.ORCID 0000-0001-6217-6501
Pedro Puerta-AlcaldeInfectious Diseases Department, Hospital Clinic of Barcelona-IDIBAPS, 08036 Barcelona, Spain.
Leyre Huete-ÁlavaInternal Medicine Department, Hospital Reina Sofía de Tudela, 31500 Tudela, Spain.
Júlia Laporte-AmargósInfectious Diseases Department, Bellvitge University Hospital, Bellvitge Biomedical Research Institute (IDIBELL), University of Barcelona, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.ORCID 0000-0001-6114-7231
Alba BergasInfectious Diseases Department, Bellvitge University Hospital, Bellvitge Biomedical Research Institute (IDIBELL), University of Barcelona, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Mariana ChumbitaInfectious Diseases Department, Hospital Clinic of Barcelona-IDIBAPS, 08036 Barcelona, Spain.
Mar MarínOncology Department, Institut Català d'Oncologia (ICO), Hospital Duran i Reynals, IDIBELL, L'Hospitalet de Llobregat, 08908 Barcelona, Spain.
Eva Domingo-DomenechHematology Department, Institut Català d'Oncologia (ICO), Hospital Duran i Reynals, IDIBELL, L'Hospitalet de Llobregat, 08908 Barcelona, Spain.ORCID 0000-0001-8907-090X
Ana María Badia-TejeroInfectious Diseases Department, Bellvitge University Hospital, Bellvitge Biomedical Research Institute (IDIBELL), University of Barcelona, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Paula Pons-OltraInfectious Diseases Department, Bellvitge University Hospital, Bellvitge Biomedical Research Institute (IDIBELL), University of Barcelona, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Carolina García-VidalCentro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Jordi CarratalàInfectious Diseases Department, Bellvitge University Hospital, Bellvitge Biomedical Research Institute (IDIBELL), University of Barcelona, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.ORCID 0000-0003-3209-2563
Carlota GudiolInfectious Diseases Department, Bellvitge University Hospital, Bellvitge Biomedical Research Institute (IDIBELL), University of Barcelona, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.ORCID 0000-0003-3095-4422
Instituto de Salud Carlos III · ESBellvitge University Hospital · ESDepartament de Salut · ESHospital Clínic de Barcelona · ESHospital Universitario Reina Sofía · ESInstitut d'Investigació Biomédica de Bellvitge · ESUniversity of Milan · IT

Funding

Centro de Investigación Biomédica en Red CB21/13/00009Centro de Investigación Biomédica en Red CB21/13/00054Centro de Investigación Biomédica en Red CB21/13/00079Centro de Investigación Biomédica en Red CB21/13/00086
6 · The paper itself

Abstract

objectivesto assess the current epidemiology, antibiotic therapy and outcomes of onco- hematological patients with bacteremic skin and soft-tissue infections (SSTIs), and to identify the risk factors for Gram-negative bacilli (GNB) infection and for early and overall mortality.

methodsepisodes of bacteremic SSTIs occurring in cancer patients at two hospitals were prospectively recorded and retrospectively analyzed.

resultsOf 164 episodes of bacteremic SSTIs, 53% occurred in patients with solid tumors and 47% with hematological malignancies. GNB represented 45.5% of all episodes, led by

conclusionsGNB bacteremic SSTI was common, particularly if corticosteroid therapy or skin necrosis. IEAT was frequent in resistant bacteria infections. Mortality occurred mainly in older patients with septic shock, resistant bacteria and IEAT. These results might guide empirical antibiotic therapy in this high-risk population.

Indexed as

antibiotic resistancebacteremiacancerPseudomonas aeruginosaskin and soft-tissue infections

Identifiers

PMID38136755
PMCPMC10740481
OpenAlexW4389675327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.