Evidence map›Paper›PMID 38136745›Full record

ReviewAntibiotics (Basel, Switzerland)2023

Optimized Treatment of Nosocomial Peritonitis.

Jan J De Waele, Federico Coccolini, Leonel Lagunes, Emilio Maseda, Stefano Rausei, Ines Rubio-Perez, Maria Theodorakopoulou, Kostoula Arvaniti

Open access · goldAbstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Temporal changes in fungal epidemiology in ICU post-operative peritonitis cases.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 5 countries.

Jan J De WaeleDepartment of Intensive Care Medicine, Ghent University Hospital, 9000 Ghent, Belgium.ORCID 0000-0003-1017-9748
Federico CoccoliniGeneral, Emergency and Trauma Surgery Department, Pisa University Hospital, 56124 Pisa, Italy.ORCID 0000-0001-6364-4186
Leonel LagunesVall d'Hebron Institut de Recerca CRIPS, 08035 Barcelona, Spain.ORCID 0000-0003-2517-8000
Emilio MasedaDepartment of Anesthesia and Critical Care, Hospital Quironsalud Valle del Henares, 28850 Madrid, Spain.ORCID 0000-0003-2898-7073
Stefano RauseiGeneral Surgery Unit, Department of Surgery, Cittiglio-Angera Hospital, ASST SetteLaghi, 21100 Varese, Italy.ORCID 0000-0002-6676-2935
Ines Rubio-PerezColorectal Surgery Unit, Department of General Surgery, Hospital Universitario La Paz, 28029 Madrid, Spain.ORCID 0000-0002-3960-6865
Maria Theodorakopoulou1st Department of Critical Care Medicine & Pulmonary Services, School of Medicine, National and Kapodistrian University of Athens, Evangelismos Hospital, 10675 Athens, Greece.ORCID 0000-0002-0385-1869
Kostoula ArvanitiDepartment of Intensive Care Medicine, Papageorgiou Hospital, 54646 Thessaloniki, Greece.ORCID 0000-0003-1171-4108
Autonomous University of San Luis Potosí · MXAzienda Ospedaliera Universitaria Pisana · ITGhent University Hospital · BEHospital Universitario La Paz · ESNational and Kapodistrian University of Athens · GRPapageorgiou General Hospital · GRUniversidad Complutense de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This comprehensive review aims to provide a practical guide for intensivists, focusing on enhancing patient care associated with nosocomial peritonitis (NP). It explores the epidemiology, diagnosis, and management of NP, a significant contributor to the mortality of surgical patients worldwide. NP is, per definition, a hospital-acquired condition and a consequence of gastrointestinal surgery or a complication of other diseases. NP, one of the most prevalent causes of sepsis in surgical Intensive Care Units (ICUs), is often associated with multi-drug resistant (MDR) bacteria and high mortality rates. Early clinical suspicion and the utilization of various diagnostic tools like biomarkers and imaging are of great importance. Microbiology is often complex, with antimicrobial resistance escalating in many parts of the world. Fungal peritonitis and its risk factors, diagnostic hurdles, and effective management approaches are particularly relevant in patients with NP. Contemporary antimicrobial strategies for treating NP are discussed, including drug resistance challenges and empirical antibiotic regimens. The importance of source control in intra-abdominal infection management, including surgical and non-surgical interventions, is also emphasized. A deeper exploration into the role of open abdomen treatment as a potential option for selected patients is proposed, indicating an area for further investigation. This review underscores the need for more research to advance the best treatment strategies for NP.

Indexed as

abdominal sepsisantibioticsantimicrobialsnosocomial infectionperitonitissepsis

Identifiers

PMID38136745
PMCPMC10740749
OpenAlexW4389481636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.