Evidence map›Paper›PMID 38136676›Full record

ArticleBiomolecules2023

Metabolic Patterns of High-Invasive and Low-Invasive Oral Squamous Cell Carcinoma Cells Using Quantitative Metabolomics and

Wenrong Jiang, Ting Zhang, Hua Zhang, Tingli Han, Ping Ji, Zhanpeng Ou

Abstract read
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wenrong JiangChongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing 401147, China.ORCID 0000-0002-8490-8467
Ting ZhangChongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing 401147, China.
Hua ZhangMinistry of Education of China International Collaborative Joint Laboratory of Reproduction and Development, Chongqing Medical University, Chongqing 400016, China.ORCID 0000-0003-3501-8385
Tingli HanMinistry of Education of China International Collaborative Joint Laboratory of Reproduction and Development, Chongqing Medical University, Chongqing 400016, China.
Ping JiChongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing 401147, China.
Zhanpeng OuChongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing 401147, China.

Funding

The National Natural Science Foundation of China 82071115, 31871464
6 · The paper itself

Abstract

Most current metabolomics studies of oral squamous cell carcinoma (OSCC) are mainly focused on identifying potential biomarkers for early screening and diagnosis, while few studies have investigated the metabolic profiles promoting metastasis. In this study, we aimed to explore the altered metabolic pathways associated with metastasis of OSCC. Here, we identified four OSCC cell models (CAL27, HN6, HSC-3, SAS) that possess different invasive heterogeneity via the transwell invasion assay and divided them into high-invasive (HN6, SAS) and low-invasive (CAL27, HSC-3) cells. Quantitative analysis and stable isotope tracing using [U-

Indexed as

Carcinoma, Squamous CellHead and Neck NeoplasmsMouth NeoplasmsCell Line, TumorFatty AcidsGlycineHumansSquamous Cell Carcinoma of Head and NeckFatty AcidsGlycinemetastasisoral squamous cell carcinoma cellsquantitative metabolomicsstable isotope tracing

Identifiers

PMID38136676
PMCPMC10742159

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.