Evidence map›Paper›PMID 38136575›Full record

ReviewBiomolecules2023

The Roles of WNT Signaling Pathways in Skin Development and Mechanical-Stretch-Induced Skin Regeneration.

Ruoxue Bai, Yaotao Guo, Wei Liu, Yajuan Song, Zhou Yu, Xianjie Ma

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Supercritical COMaterials today. Bio · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ruoxue BaiDepartment of Plastic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.ORCID 0009-0004-2322-4717
Yaotao GuoDepartment of Plastic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.ORCID 0000-0002-3076-7486
Wei LiuDepartment of Plastic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.
Yajuan SongDepartment of Plastic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.
Zhou YuDepartment of Plastic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.ORCID 0000-0002-2358-0090
Xianjie MaDepartment of Plastic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.
Xijing Hospital · CN

Funding

Foundation of Xijing Hospital Grants XJZT21CM33National Natural Science Foundation of China 81971851National Natural Science Foundation of China 82172229Natural Science Basic Research Plan in Shaanxi Province of China 2022JM-600
6 · The paper itself

Abstract

The WNT signaling pathway plays a critical role in a variety of biological processes, including development, adult tissue homeostasis maintenance, and stem cell regulation. Variations in skin conditions can influence the expression of the WNT signaling pathway. In light of the above, a deeper understanding of the specific mechanisms of the WNT signaling pathway in different physiological and pathological states of the skin holds the potential to significantly advance clinical treatments of skin-related diseases. In this review, we present a comprehensive analysis of the molecular and cellular mechanisms of the WNT signaling pathway in skin development, wound healing, and mechanical stretching. Our review sheds new light on the crucial role of the WNT signaling pathway in the regulation of skin physiology and pathology.

Indexed as

Skin DiseasesWnt Signaling PathwayAdultHumansSkinStem CellsWound Healingmechanical stretchskin developmentWNT signaling pathwaywound repairβ-catenin

Identifiers

PMID38136575
PMCPMC10741662
OpenAlexW4388977595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.