Evidence map›Paper›PMID 38136435›Full record

ReviewCancers2023

Radiomics for Differentiation of Pediatric Posterior Fossa Tumors: A Meta-Analysis and Systematic Review of the Literature.

Alexandru Garaba, Francesco Ponzio, Eleonora Agata Grasso, Waleed Brinjikji, Marco Maria Fontanella, Lucio De Maria

Abstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. The role of machine learning, deep learning, and MRI findings in the classification of pediatric posterior fossa tumors.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexandru GarabaDepartment of Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, 25121 Brescia, Italy.ORCID 0000-0002-9003-6351
Francesco PonzioInteruniversity Department of Regional and Urban Studies and Planning, Politecnico di Torino, 10129 Torino, Italy.ORCID 0000-0002-8472-8247
Eleonora Agata GrassoDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA 19146, USA.
Waleed BrinjikjiDepartment of Neurosurgery and Interventional Neuroradiology, Mayo Clinic, Rochester, MN 55905, USA.
Marco Maria FontanellaDepartment of Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, 25121 Brescia, Italy.ORCID 0000-0002-4023-1909
Lucio De MariaDepartment of Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, 25121 Brescia, Italy.ORCID 0000-0003-4062-5665

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo better define the overall performance of the current radiomics-based models for the discrimination of pediatric posterior fossa tumors.

methodsA comprehensive literature search of the databases PubMed, Ovid MEDLINE, Ovid EMBASE, Web of Science, and Scopus was designed and conducted by an experienced librarian. We estimated overall sensitivity (SEN) and specificity (SPE). Event rates were pooled across studies using a random-effects meta-analysis, and the χ

resultsOverall SEN and SPE for differentiation between MB, PA, and EP were found to be promising, with SEN values of 93% (95% CI = 0.88-0.96), 83% (95% CI = 0.66-0.93), and 85% (95% CI = 0.71-0.93), and corresponding SPE values of 87% (95% CI = 0.82-0.90), 95% (95% CI = 0.90-0.98) and 90% (95% CI = 0.84-0.94), respectively. For MB, there is a better trend for LR classifiers, while textural features are the most used and the best performing (ACC 96%). As for PA and EP, a synergistic employment of LR and NN classifiers, accompanied by geometrical or morphological features, demonstrated superior performance (ACC 94% and 96%, respectively).

conclusionsThe diagnostic performance is high, making radiomics a helpful method to discriminate these tumor types. In the forthcoming years, we expect even more precise models.

Indexed as

deep learningmachine learningmeta-analysispediatric tumorsposterior fossaradiomicssystematic review

Identifiers

PMID38136435
PMCPMC10742196

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.