Evidence map›Paper›PMID 38136349›Full record

ArticleCancers2023

Pediatric Atypical Melanocytic Proliferations: Single-Site Retrospective Cohort Assessment of Treatment and Long-Term Follow-Up.

Emily Hatheway Marshall, Gabriella Alvarez, Bangchen Wang, Jennifer Crimmins, Michelle M Schneider, M Angelica Selim, Rami N Al-Rohil

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Genital Disorders in Children: What Does a Biopsy Bring?Dermatopathology (Basel, Switzerland) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Emily Hatheway MarshallDepartment of Pathology, Mass General Brigham, Boston, MA 02130, USA.
Gabriella AlvarezDepartment of Internal Medicine, The University of Texas Health Sciences Center at Houston, Houston, TX 77030, USA.ORCID 0000-0003-2970-2762
Bangchen WangDepartment of Pathology, Duke University Medical Center, Durham, NC 27710, USA.ORCID 0000-0002-0942-7858
Jennifer CrimminsDepartment of Pathology, Duke University Medical Center, Durham, NC 27710, USA.
Michelle M SchneiderDepartment of Pathology, Duke University Medical Center, Durham, NC 27710, USA.
M Angelica SelimDepartment of Pathology, Duke University Medical Center, Durham, NC 27710, USA.
Rami N Al-RohilDepartment of Pathology, Duke University Medical Center, Durham, NC 27710, USA.ORCID 0000-0002-9431-0530
Duke Medical Center · USMass General Brigham · USThe University of Texas Health Science Center at Houston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atypical and malignant cutaneous tumors are understudied in the pediatric population, with limited data on long-term follow-up. This study examines pediatric (0-18 years) atypical melanocytic proliferations over a twenty-year period (January 2002-December2022) using the EPIC SlicerDicer at our institution. Over a twenty-year period, there were 55 cases of pediatric melanoma (53 patients). The median follow-up time was 8 years, 11 months. A proportion of 96% were treated with wide local excision (WLE), and 47% had a sentinel lymph node biopsy (SLNB) (35% positive rate). There were 101 atypical Spitz tumor cases (85% atypical Spitz tumors, 15% Spitz melanoma), with a median follow-up duration of 9 years. A proportion of 77% were treated with WLE (with one patient dying of metastatic disease). There were 10 cases of atypical melanocytic proliferations not otherwise specified, including 5 pigmented epithelioid melanocytomas (PEM), 4 deep-penetrating nevi, and 1 atypical cellular blue nevus. This study adds to the growing body of knowledge on pediatric atypical cutaneous melanocytic proliferations, aligning with many described characteristics such as disease location and overall survival rates, with distinct exceptions (higher melanoma positive SLNB rate, lower atypical Spitz tumor WLE rate, and a case of fatal metastatic atypical Spitz tumor).

Indexed as

deep penetrating nevuspediatric melanomapigmented epithelioid melanocytomaSpitz tumor

Identifiers

PMID38136349
PMCPMC10741983
OpenAlexW4389624297

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.